ID   CU30_BOMMO              Reviewed;         239 AA.
AC   Q08738;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2004, sequence version 2.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Larval cuticle protein LCP-30;
DE   Flags: Precursor;
GN   Name=LCP30;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], AND PROTEIN SEQUENCE OF 17-26.
RC   STRAIN=Tokai X Asahi; TISSUE=Larval epidermis, and Larval fat body;
RX   PubMed=8193166; DOI=10.1016/0167-4781(94)90101-5;
RA   Nakato H., Shofuda K., Izumi S., Tomino S.;
RT   "Structure and developmental expression of a larval cuticle protein gene of
RT   the silkworm, Bombyx mori.";
RL   Biochim. Biophys. Acta 1218:64-74(1994).
RN   [2]
RP   SEQUENCE REVISION TO 130 AND C-TERMINUS.
RA   Togawa T.;
RL   Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Major cuticle protein of the integuments. May interact with
CC       both chitin and epidermal cells to form stable cuticular structures.
CC   -!- DEVELOPMENTAL STAGE: Exists in integuments throughout the larval stages
CC       and disappears at larval-pupal ecdysis. Present in lower amount adult
CC       cuticle after eclosion.
CC   -!- INDUCTION: By juvenile hormone.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA52369.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; X74320; CAA52368.2; -; mRNA.
DR   EMBL; X74321; CAA52369.1; ALT_SEQ; Genomic_DNA.
DR   PIR; S45302; S45302.
DR   RefSeq; NP_001037490.1; NM_001044025.1.
DR   AlphaFoldDB; Q08738; -.
DR   STRING; 7091.BGIBMGA000329-TA; -.
DR   GeneID; 693048; -.
DR   KEGG; bmor:693048; -.
DR   CTD; 693048; -.
DR   eggNOG; ENOG502S88E; Eukaryota.
DR   HOGENOM; CLU_811906_0_0_1; -.
DR   InParanoid; Q08738; -.
DR   OrthoDB; 1507534at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR   InterPro; IPR000618; Insect_cuticle.
DR   Pfam; PF00379; Chitin_bind_4; 1.
DR   PRINTS; PR00947; CUTICLE.
DR   PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR   PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE   1: Evidence at protein level;
KW   Cuticle; Direct protein sequencing; Reference proteome; Signal.
FT   SIGNAL          1..16
FT                   /evidence="ECO:0000269|PubMed:8193166"
FT   CHAIN           17..239
FT                   /note="Larval cuticle protein LCP-30"
FT                   /id="PRO_0000006406"
FT   DOMAIN          172..239
FT                   /note="Chitin-binding type R&R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
FT   REGION          48..73
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           73..75
FT                   /note="Cell attachment site"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   239 AA;  25690 MW;  FE3BA96BAABD3594 CRC64;
     MRVFLAICLS LTVALAAETG KYTPFQYNRV YSTVSPFVYK PGRYVADPGR YDPSRDNSGR
     YIPDNSGAYN GDRGDRGAAG GFYTGSGTAG GPGGAYVGTK EDLSKYLGDA YKGSSIVPLP
     VVKPTIPVPV TPTYVASKVV TPTYVASKVV PPSGAGYDYK YGIIRYDNDV APEGYHYLYE
     TENKILAEEA GKVENIGTEN EGIKVKGFYE YVGPDGVTYR VDYTADENGF VADGAHIPK