ID   CU66_HYACE              Reviewed;         129 AA.
AC   P45590;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Larval/pupal rigid cuticle protein 66;
DE   AltName: Full=HCCP66;
DE   Flags: Precursor;
GN   Name=CP66;
OS   Hyalophora cecropia (Cecropia moth) (Samia cecropia).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Saturniidae; Saturniinae; Attacini; Hyalophora.
OX   NCBI_TaxID=7123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 18-43 AND
RP   78-108.
RC   TISSUE=Epidermis;
RX   PubMed=8025561; DOI=10.1016/0965-1748(94)90035-3;
RA   Lampe D.J., Willis J.H.;
RT   "Characterization of a cDNA and gene encoding a cuticular protein from
RT   rigid cuticles of the giant silkmoth, Hyalophora cecropia.";
RL   Insect Biochem. Mol. Biol. 24:419-435(1994).
CC   -!- FUNCTION: Component of the rigid cuticle of the larva and pupa of
CC       Hyalophora cecropia.
CC   -!- TISSUE SPECIFICITY: Expressed in larval wing disc, forewing disc,
CC       diapausing wing, adult wing, and in very low amounts in fat body and
CC       testes.
CC   -!- DEVELOPMENTAL STAGE: Mostly present in young pupal wings and larval
CC       tubercles. Faintly present in younger than 24 hours old pupal forewing
CC       and hindwing. Weakly detected in hindwing and tubercles.
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DR   EMBL; L13971; AAC37204.1; -; Genomic_DNA.
DR   AlphaFoldDB; P45590; -.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
DR   InterPro; IPR031311; CHIT_BIND_RR_consensus.
DR   InterPro; IPR000618; Insect_cuticle.
DR   Pfam; PF00379; Chitin_bind_4; 1.
DR   PROSITE; PS00233; CHIT_BIND_RR_1; 1.
DR   PROSITE; PS51155; CHIT_BIND_RR_2; 1.
PE   1: Evidence at protein level;
KW   Cuticle; Direct protein sequencing; Signal.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000269|PubMed:8025561"
FT   CHAIN           18..129
FT                   /note="Larval/pupal rigid cuticle protein 66"
FT                   /id="PRO_0000006386"
FT   DOMAIN          18..90
FT                   /note="Chitin-binding type R&R"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00497"
FT   CONFLICT        105
FT                   /note="Y -> F (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        108
FT                   /note="S -> F (in Ref. 1; AA sequence)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   129 AA;  13878 MW;  8914FEC3F940DCC6 CRC64;
     MLVKFVACFV FVAVASASDF SSFSYGVADP STGDFKSQIE SRLGDNVQGQ YSLLESDGTQ
     RTVDYAAGSE GFNAVVRKDP ALIAAAPYIT APYGYAVPYA YTSPYGISNL ANYRALKFAS
     ALPYSRVFF