CUB1_SCHPO
ID CUB1_SCHPO Reviewed; 457 AA.
AC Q9P6K3;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=CUB1 family protein C30C2.08 {ECO:0000305};
GN ORFNames=SPAC30C2.08;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Involved in bleomycin tolerance with links to DNA repair
CC and/or proteasome function. {ECO:0000250|UniProtKB:Q08977}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the CUB1 family. {ECO:0000305}.
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DR EMBL; CU329670; CAB90795.1; -; Genomic_DNA.
DR RefSeq; NP_594660.1; NM_001020089.2.
DR AlphaFoldDB; Q9P6K3; -.
DR BioGRID; 279494; 5.
DR STRING; 4896.SPAC30C2.08.1; -.
DR iPTMnet; Q9P6K3; -.
DR MaxQB; Q9P6K3; -.
DR PaxDb; Q9P6K3; -.
DR PRIDE; Q9P6K3; -.
DR EnsemblFungi; SPAC30C2.08.1; SPAC30C2.08.1:pep; SPAC30C2.08.
DR GeneID; 2543060; -.
DR KEGG; spo:SPAC30C2.08; -.
DR PomBase; SPAC30C2.08; -.
DR VEuPathDB; FungiDB:SPAC30C2.08; -.
DR eggNOG; ENOG502QPV0; Eukaryota.
DR HOGENOM; CLU_026648_1_0_1; -.
DR InParanoid; Q9P6K3; -.
DR OMA; KQDRTTY; -.
DR PhylomeDB; Q9P6K3; -.
DR PRO; PR:Q9P6K3; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR InterPro; IPR018810; UPF0662.
DR PANTHER; PTHR28086; PTHR28086; 1.
DR Pfam; PF10303; DUF2408; 3.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..457
FT /note="CUB1 family protein C30C2.08"
FT /id="PRO_0000352784"
FT COILED 119..174
FT /evidence="ECO:0000255"
FT COILED 418..448
FT /evidence="ECO:0000255"
SQ SEQUENCE 457 AA; 52691 MW; B33F3E553C00E36C CRC64;
MMSYEPAEPV PVEEQPILEK LIGIRQRLAV LKRDRTRFIE KNEVFHLKDE LVEQMNLLDS
RRSTNSTRTI VDSQLEDCLH LLSLFYLAIG RNNDLPAFFV QLGTVRRLLE YNLEGACYTQ
NDLKPLKERL ERIRAAIVEG SKKEDASPVV VKYLNNKLAV CDRNYSEAQH NISKISPELI
GIQTRLVSIH RQIDGFAVRP TSDPGFIDRT MEQLKEIEEM KDSNGMFCDA DHVPLQGQEL
CNGILEECFS FLEDAKTKEG LSDEMKSSPK LQQIYHRLDE LLNKLKHLTL THRWTLRETD
LYVYRASLAE IDSMRIDGQF LDEQGNAPAG QRILLYLLRR CYAYIYQLLS SSEPVSEELM
AVHNQLRTVK RCLLEVQRSG GICSERDLYP YQMKLASLEN LRVNGKFLAS DHSVPEGQEL
VNSLLTQCHQ LIEELRDEKH QHDIEEREGS ENTDGNL