33VP_CHENC
ID 33VP_CHENC Reviewed; 246 AA.
AC Q7M3V1; B6VQ30;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=33kDa venom protein;
DE Flags: Precursor;
OS Chelonus sp. nr. curvimaculatus (Parasitic wasp).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Parasitoida;
OC Ichneumonoidea; Braconidae; Cheloninae; Chelonus; unclassified Chelonus.
OX NCBI_TaxID=132888;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Venom gland;
RX PubMed=1378841; DOI=10.1016/s0021-9258(18)42121-7;
RA Jones D., Sawicki G., Wozniak M.;
RT "Sequence, structure, and expression of a wasp venom protein with a
RT negatively charged signal peptide and a novel repeating internal
RT structure.";
RL J. Biol. Chem. 267:14871-14878(1992).
RN [2]
RP PROTEIN SEQUENCE OF 21-40.
RC TISSUE=Venom;
RX PubMed=2383579; DOI=10.1016/0304-4165(90)90170-2;
RA Taylor T., Jones D.;
RT "Isolation and characterization of the 32.5 kDa protein from the venom of
RT an endoparasitic wasp.";
RL Biochim. Biophys. Acta 1035:37-43(1990).
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
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DR EMBL; M92086; ACI70208.1; -; mRNA.
DR PIR; A42876; A42876.
DR AlphaFoldDB; Q7M3V1; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Repeat; Secreted; Signal.
FT SIGNAL 1..20
FT /evidence="ECO:0000269|PubMed:2383579"
FT CHAIN 21..246
FT /note="33kDa venom protein"
FT /id="PRO_0000408021"
FT REPEAT 83..96
FT /note="1"
FT REPEAT 97..110
FT /note="2"
FT REPEAT 111..124
FT /note="3"
FT REPEAT 125..138
FT /note="4"
FT REPEAT 139..152
FT /note="5"
FT REPEAT 153..166
FT /note="6"
FT REPEAT 167..180
FT /note="7"
FT REPEAT 181..187
FT /note="8; half-length"
FT REPEAT 188..201
FT /note="9"
FT REPEAT 202..215
FT /note="10"
FT REPEAT 216..229
FT /note="11"
FT REPEAT 230..243
FT /note="12"
FT REGION 83..243
FT /note="12 X approximate tandem repeats of
FT [AV][DE]X[VL]SGSX[DE]QX[KR]X[ST]"
FT REGION 88..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 106..176
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 246 AA; 26029 MW; C33F39D992032E05 CRC64;
MAGKEVIFIM ALFIAVESSP IFSFDDLVCP SVTSLRVNVE KNECSTKKDC GRNLCCENQN
KINVCVGGIM PLPKPNLDVN NIGGAVSESV KQKRETAESL SGSFDKEKAS AENLSGSFDQ
QKSSVDEKSG SVGQQKGAVE GQSGSGEQRR ETAESQSGSV DQEKASAENL SGSIDKQKVT
VEEKSEPAQG QSGSVKQKRK TTENVSGSLD QEKASAESLS GSFDQQKSSV DEKSGSVGND
DDISVQ