ID   CUE2B_XENLA             Reviewed;         269 AA.
AC   Q68F60;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 48.
DE   RecName: Full=CUE domain-containing protein 2-B;
GN   Name=cuedc2-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May play a role in targeting proteins for ubiquitination and
CC       subsequent proteasomal degradation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- PTM: Phosphorylated. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CUEDC2 family. {ECO:0000305}.
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DR   EMBL; BC079984; AAH79984.1; -; mRNA.
DR   RefSeq; NP_001087476.1; NM_001094007.1.
DR   RefSeq; XP_018080047.1; XM_018224558.1.
DR   AlphaFoldDB; Q68F60; -.
DR   BioGRID; 104160; 1.
DR   IntAct; Q68F60; 1.
DR   GeneID; 447300; -.
DR   KEGG; xla:447300; -.
DR   CTD; 447300; -.
DR   Xenbase; XB-GENE-6254018; cuedc2.L.
DR   OMA; VICEWIY; -.
DR   OrthoDB; 1410219at2759; -.
DR   Proteomes; UP000186698; Chromosome 7L.
DR   Bgee; 447300; Expressed in gastrula and 17 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   CDD; cd14367; CUE_CUED2; 1.
DR   InterPro; IPR039805; CUE_CUED2.
DR   InterPro; IPR039784; CUEDC2.
DR   PANTHER; PTHR12493; PTHR12493; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Phosphoprotein; Reference proteome;
KW   Ubl conjugation pathway.
FT   CHAIN           1..269
FT                   /note="CUE domain-containing protein 2-B"
FT                   /id="PRO_0000282997"
FT   DOMAIN          131..174
FT                   /note="CUE"
FT   REGION          110..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   269 AA;  30036 MW;  8EB7C0159F1D18DB CRC64;
     MALEKIIRES LTGFLQCHIA HADLSALDEV FCAYVTGVLE ELGSQNSSEE DFEMESFVEM
     LEGYIPGFSE ISSEKVYDML FELSGRLSEA RGTENVSPNP TVEVSFMTPA SPSEKTATEP
     LEGAVAQDKD DPKTGVDLLL EIFPSCTITQ AQTALSMAKG DLEDAVQIIV DGKVIADNHS
     GSKDMQGAPK IEDLKDFILQ KYMLVDTEDD KKTYRPVAPK EAPKKMIRYI DNQVVSTKGE
     RYKDIKKPES EEMKKTYINL KPARKYKFH