CUE5_SCHPO
ID CUE5_SCHPO Reviewed; 569 AA.
AC O14319;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=CUE domain-containing protein 5;
GN ORFNames=SPBC16E9.02c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329671; CAB16895.1; -; Genomic_DNA.
DR PIR; T39577; T39577.
DR RefSeq; NP_595784.1; NM_001021685.2.
DR AlphaFoldDB; O14319; -.
DR SMR; O14319; -.
DR BioGRID; 276359; 13.
DR STRING; 4896.SPBC16E9.02c.1; -.
DR iPTMnet; O14319; -.
DR MaxQB; O14319; -.
DR PaxDb; O14319; -.
DR PRIDE; O14319; -.
DR EnsemblFungi; SPBC16E9.02c.1; SPBC16E9.02c.1:pep; SPBC16E9.02c.
DR GeneID; 2539809; -.
DR KEGG; spo:SPBC16E9.02c; -.
DR PomBase; SPBC16E9.02c; -.
DR VEuPathDB; FungiDB:SPBC16E9.02c; -.
DR eggNOG; KOG0504; Eukaryota.
DR HOGENOM; CLU_034772_0_0_1; -.
DR InParanoid; O14319; -.
DR PhylomeDB; O14319; -.
DR PRO; PR:O14319; -.
DR Proteomes; UP000002485; Chromosome II.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0043130; F:ubiquitin binding; ISM:PomBase.
DR GO; GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:GO_Central.
DR GO; GO:0007165; P:signal transduction; ISS:PomBase.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR CDD; cd14372; CUE_Cue5p_like; 1.
DR InterPro; IPR003892; CUE.
DR InterPro; IPR041807; Cue5/Don1_CUE.
DR InterPro; IPR009060; UBA-like_sf.
DR Pfam; PF02845; CUE; 1.
DR SMART; SM00546; CUE; 1.
DR SUPFAM; SSF46934; SSF46934; 1.
DR PROSITE; PS51140; CUE; 1.
PE 4: Predicted;
KW Cytoplasm; Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..569
FT /note="CUE domain-containing protein 5"
FT /id="PRO_0000310345"
FT DOMAIN 17..60
FT /note="CUE"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00468"
FT REGION 67..139
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 175..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 311..569
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 83..119
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 253..275
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 311..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..370
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 371..385
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 395..569
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 569 AA; 63726 MW; 2D1374B0E05660E5 CRC64;
MASEQSNPRL PRRPPYMAEK ARATLKEAFP NTDDAIIRAV LAASGYKLEP AFNALLGLSD
PQVAEEMEQA ETSYAYDTAA HDDPVQRQLE EDERCARELA NRYNSHRPER RRKTNNDRRN
YPPQNRTAKP NDNDGDDYSF FEDDLPVIKD TFMRGFQSFK QRSMEWVENI ASKFDGEEED
DDDEKYSAPS KIYPSPRRST AATLESAYEE RPPSLPRRKP SRPGTAITLP PYESDPHMLN
EKDFERLRLE SSSSPMMRRS SLNSNRRSVE SSSSAAFVEG QSFILDSNGA IEVANSAFAL
DDSDLESAYN EELEMKKDTS KPTASTKEVV VEKKPDESRK QAARTLETVS EEQMGSSNAK
SKVLTSEPKD STSVEAEKTE TDEPAVGKGA SDVSDTAEIS EKTEAKNADS EANLEEKSDV
GEEKESKDEN NKASLHKDVE EKDTKITNED TGKTETDVKA KETDSIEAND KDEKTDSKET
EDKVEETESK EADVKAKETD SIEVDDKEEK TDSKETADKV EQTDSKDTNE KPAKDDNKEA
NEKAEKVDSK DVKEKIEEAA DLQNSGKET
