ID   CUED1_MOUSE             Reviewed;         388 AA.
AC   Q8R3V6; Q5SXC2;
DT   10-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT   27-JUL-2011, sequence version 2.
DT   03-AUG-2022, entry version 117.
DE   RecName: Full=CUE domain-containing protein 1;
GN   Name=Cuedc1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
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DR   EMBL; AL593853; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BC024476; AAH24476.1; -; mRNA.
DR   EMBL; BC029708; AAH29708.1; -; mRNA.
DR   CCDS; CCDS25226.1; -.
DR   RefSeq; NP_932130.2; NM_198013.3.
DR   AlphaFoldDB; Q8R3V6; -.
DR   SMR; Q8R3V6; -.
DR   BioGRID; 222179; 1.
DR   STRING; 10090.ENSMUSP00000018522; -.
DR   iPTMnet; Q8R3V6; -.
DR   PhosphoSitePlus; Q8R3V6; -.
DR   MaxQB; Q8R3V6; -.
DR   PaxDb; Q8R3V6; -.
DR   PRIDE; Q8R3V6; -.
DR   ProteomicsDB; 285433; -.
DR   Antibodypedia; 18339; 101 antibodies from 24 providers.
DR   Ensembl; ENSMUST00000018522; ENSMUSP00000018522; ENSMUSG00000018378.
DR   GeneID; 103841; -.
DR   KEGG; mmu:103841; -.
DR   UCSC; uc007kvg.2; mouse.
DR   CTD; 404093; -.
DR   MGI; MGI:2144281; Cuedc1.
DR   VEuPathDB; HostDB:ENSMUSG00000018378; -.
DR   eggNOG; KOG4588; Eukaryota.
DR   GeneTree; ENSGT00390000006762; -.
DR   HOGENOM; CLU_064865_0_0_1; -.
DR   InParanoid; Q8R3V6; -.
DR   OMA; TDFKTMF; -.
DR   OrthoDB; 1485571at2759; -.
DR   PhylomeDB; Q8R3V6; -.
DR   TreeFam; TF324332; -.
DR   BioGRID-ORCS; 103841; 4 hits in 74 CRISPR screens.
DR   ChiTaRS; Cuedc1; mouse.
DR   PRO; PR:Q8R3V6; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; Q8R3V6; protein.
DR   Bgee; ENSMUSG00000018378; Expressed in retinal neural layer and 63 other tissues.
DR   ExpressionAtlas; Q8R3V6; baseline and differential.
DR   Genevisible; Q8R3V6; MM.
DR   GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR   CDD; cd14366; CUE_CUED1; 1.
DR   InterPro; IPR003892; CUE.
DR   InterPro; IPR040195; CUE_CUED1.
DR   InterPro; IPR040192; CUEDC1.
DR   InterPro; IPR009060; UBA-like_sf.
DR   PANTHER; PTHR13467; PTHR13467; 1.
DR   Pfam; PF02845; CUE; 1.
DR   SMART; SM00546; CUE; 1.
DR   SUPFAM; SSF46934; SSF46934; 1.
DR   PROSITE; PS51140; CUE; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..388
FT                   /note="CUE domain-containing protein 1"
FT                   /id="PRO_0000079560"
FT   DOMAIN          50..93
FT                   /note="CUE"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00468"
FT   REGION          1..45
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          152..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          196..225
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          270..302
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          369..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        31..45
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        272..301
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        277
FT                   /note="N -> Y (in Ref. 2; AAH29708/AAH24476)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   388 AA;  42780 MW;  AB292640F813D53A CRC64;
     MTSLFRRSSS GSGGGGATGA RGAGTGAGDG STAPQELNNS RPARQVRRLE FNQAMDDFKT
     MFPNMDYDII ECVLRANSGA VDATIDQLLQ MNLEAGGGSA YEDSSDSEDS IPPEILERTL
     EPDSSEEEPP PVYSPPAYHM HVFDRPYLMA PPTPPPRIDV PGSGQPASQR RYRNWNPPLL
     GSLPDDFLRI LPQQMDSIQG HPGGSKPMSG EGGPPPAPGP MACDQDSRWK QYLEDERIAL
     FLQNEEFMKE LQRNRDFLLA LERDRLKYES QKSKSNNAAV GNDGGFPSSV PGTSETNPTV
     SEDALFRDKL KHMGKSTRRK LFELARAFSE KTKMRKSKKK HLPKLQSLGA AASTANLLDD
     VEGHAYEEDF RGRRQEVPKV EEALREGQ