CUF1_TENMO
ID CUF1_TENMO Reviewed; 162 AA.
AC Q9TXD9; Q9TXE0; Q9TXE1;
DT 31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 43.
DE RecName: Full=Larval cuticle protein F1;
DE AltName: Full=Tml-F1;
OS Tenebrio molitor (Yellow mealworm beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrio.
OX NCBI_TaxID=7067;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE (F1A; F1B AND F1C), AND MASS SPECTROMETRY.
RC TISSUE=Cuticle {ECO:0000269|PubMed:7795523};
RX PubMed=7795523; DOI=10.1002/pro.5560040306;
RA Haebel S., Jensen C., Andersen S.O., Roepstorff P.;
RT "Isoforms of a cuticular protein from larvae of the meal beetle, Tenebrio
RT molitor, studied by mass spectrometry in combination with Edman degradation
RT and two-dimensional polyacrylamide gel electrophoresis.";
RL Protein Sci. 4:394-404(1995).
CC -!- FUNCTION: Component of the larval cuticle. {ECO:0000305}.
CC -!- DOMAIN: The tetrapeptide (A-A-P-[AV]) repeats found throughout the
CC protein are also present in many proteins constituting the protective
CC envelope of other species. {ECO:0000305}.
CC -!- MASS SPECTROMETRY: Mass=14919.9; Method=Electrospray; Note=Allele F1C.;
CC Evidence={ECO:0000269|PubMed:7795523};
CC -!- POLYMORPHISM: The following alleles of F1 are known: F1C, F1B and F1A.
CC The sequence shown is that of F1C. {ECO:0000269|PubMed:7795523}.
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DR AlphaFoldDB; Q9TXD9; -.
DR GO; GO:0008010; F:structural constituent of chitin-based larval cuticle; NAS:UniProtKB.
PE 1: Evidence at protein level;
KW Cuticle; Direct protein sequencing; Repeat.
FT CHAIN 1..162
FT /note="Larval cuticle protein F1"
FT /id="PRO_0000196135"
FT REPEAT 27..30
FT /note="1"
FT /evidence="ECO:0000305"
FT REPEAT 43..46
FT /note="2"
FT /evidence="ECO:0000305"
FT REPEAT 59..62
FT /note="3"
FT /evidence="ECO:0000305"
FT REPEAT 75..78
FT /note="4"
FT /evidence="ECO:0000305"
FT VARIANT 11..14
FT /note="Missing (in allele F1B)"
FT /evidence="ECO:0000269|PubMed:7795523"
FT VARIANT 40..47
FT /note="Missing (in allele F1A)"
FT /evidence="ECO:0000269|PubMed:7795523"
SQ SEQUENCE 162 AA; 14919 MW; D7F4B351739654DB CRC64;
GLIGAPIAAP IAAPLATSVV STRTIHAAPV AVAHAAPLAV AHAAPVAVAH AAPLAVAHAA
PVAVAHAAPL AVAHAAPAIA YGGYGSGLIG GAYGGGLIGS RSLYGGYGSG LGIARSTPGG
YGSGLIGGAY GSGLIGGGLY GARYGLGAPA LGHGLIGGAH LY