CUL1_ORYSJ
ID CUL1_ORYSJ Reviewed; 744 AA.
AC Q5ZC88; Q7XB92; Q93VH7; Q94I77;
DT 08-MAY-2019, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Cullin-1 {ECO:0000305};
DE Short=OsCUL1 {ECO:0000303|PubMed:24616269};
DE AltName: Full=OsCUL1-1 {ECO:0000303|PubMed:29892794};
GN Name=CUL1 {ECO:0000303|PubMed:24616269};
GN Synonyms=CUL1-1 {ECO:0000303|PubMed:29892794};
GN OrderedLocusNames=Os01g0369000 {ECO:0000312|EMBL:BAF04962.1},
GN LOC_Os01g27150 {ECO:0000305};
GN ORFNames=OsJ_01786 {ECO:0000312|EMBL:EEE54581.1},
GN OSJNBa0010P20.16 {ECO:0000312|EMBL:AAK53839.1},
GN P0043B10.31 {ECO:0000312|EMBL:BAD61452.1},
GN P0560B06.30 {ECO:0000312|EMBL:BAB64762.1};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=cv. Lemont;
RA Huang E.N., de la Bastide M., Vil D.M., Preston R.R., Spiegel L.A.,
RA See L.H., Shah R., Matero A., O'Shaughnessy A., Rodriguez M., Shekher M.,
RA Swaby I., Schutz K., Habermann K., Parnell L.D., Nascimento L.U.,
RA Dedhia N.N., McCombie W.R.;
RT "Genomic Sequence For Oryza sativa Clone 10P20, Lemont Strain, Complete
RT Sequence.";
RL Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
RA Yao Q., Peng R., Xiong A.;
RT "Rice cul-1 is required for cell cycle.";
RL Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447438; DOI=10.1038/nature01184;
RA Sasaki T., Matsumoto T., Yamamoto K., Sakata K., Baba T., Katayose Y.,
RA Wu J., Niimura Y., Cheng Z., Nagamura Y., Antonio B.A., Kanamori H.,
RA Hosokawa S., Masukawa M., Arikawa K., Chiden Y., Hayashi M., Okamoto M.,
RA Ando T., Aoki H., Arita K., Hamada M., Harada C., Hijishita S., Honda M.,
RA Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., Ito S., Ito T.,
RA Ito Y., Ito Y., Iwabuchi A., Kamiya K., Karasawa W., Katagiri S.,
RA Kikuta A., Kobayashi N., Kono I., Machita K., Maehara T., Mizuno H.,
RA Mizubayashi T., Mukai Y., Nagasaki H., Nakashima M., Nakama Y.,
RA Nakamichi Y., Nakamura M., Namiki N., Negishi M., Ohta I., Ono N., Saji S.,
RA Sakai K., Shibata M., Shimokawa T., Shomura A., Song J., Takazaki Y.,
RA Terasawa K., Tsuji K., Waki K., Yamagata H., Yamane H., Yoshiki S.,
RA Yoshihara R., Yukawa K., Zhong H., Iwama H., Endo T., Ito H., Hahn J.H.,
RA Kim H.-I., Eun M.-Y., Yano M., Jiang J., Gojobori T.;
RT "The genome sequence and structure of rice chromosome 1.";
RL Nature 420:312-316(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [5]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [6]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [8]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [9]
RP INTERACTION WITH D3.
RX PubMed=24616269; DOI=10.1093/pcp/pcu045;
RA Zhao J., Wang T., Wang M., Liu Y., Yuan S., Gao Y., Yin L., Sun W.,
RA Peng L., Zhang W., Wan J., Li X.;
RT "DWARF3 participates in an SCF complex and associates with DWARF14 to
RT suppress rice shoot branching.";
RL Plant Cell Physiol. 55:1096-1109(2014).
RN [10]
RP NEDDYLATION.
RX PubMed=27137867; DOI=10.1038/srep25485;
RA Tan S., Liu F., Pan X.X., Zang Y.P., Jin F., Zu W.X., Qi X.T., Xiao W.,
RA Yin L.P.;
RT "CSN6, a subunit of the COP9 signalosome, is involved in early response to
RT iron deficiency in Oryza sativa.";
RL Sci. Rep. 6:25485-25485(2016).
RN [11]
RP IDENTIFICATION IN THE SCF COMPLEX.
RX PubMed=28494021; DOI=10.1371/journal.pone.0177518;
RA Tao T., Zhou C.J., Wang Q., Chen X.R., Sun Q., Zhao T.Y., Ye J.C., Wang Y.,
RA Zhang Z.Y., Zhang Y.L., Guo Z.J., Wang X.B., Li D.W., Yu J.L., Han C.G.;
RT "Rice black streaked dwarf virus P7-2 forms a SCF complex through binding
RT to Oryza sativa SKP1-like proteins, and interacts with GID2 involved in the
RT gibberellin pathway.";
RL PLoS ONE 12:E0177518-E0177518(2017).
RN [12]
RP TISSUE SPECIFICITY, AND INDUCTION.
RX PubMed=29892794; DOI=10.1007/s13258-017-0622-8;
RA Kim S.H., Woo O.G., Jang H., Lee J.H.;
RT "Characterization and comparative expression analysis of CUL1 genes in
RT rice.";
RL Genes Genomics 40:233-241(2018).
CC -!- FUNCTION: Involved in ubiquitination and subsequent proteasomal
CC degradation of target proteins. {ECO:0000250|UniProtKB:Q94AH6}.
CC -!- SUBUNIT: Part of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein
CC ligase complex (PubMed:28494021). Is able to form the SCF complex
CC together with SKP1 and the rice black streaked dwarf virus RBSDV
CC protein P7-2 (PubMed:28494021). Interacts with D3 (PubMed:24616269).
CC {ECO:0000269|PubMed:24616269, ECO:0000269|PubMed:28494021}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5ZC88-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5ZC88-2; Sequence=VSP_060100;
CC -!- TISSUE SPECIFICITY: Expressed in dry seeds and coleoptiles.
CC {ECO:0000269|PubMed:29892794}.
CC -!- INDUCTION: Induced by abscisic acid, heat shock, salt stress and
CC drought stress. {ECO:0000269|PubMed:29892794}.
CC -!- PTM: Neddylated (rubylated) (PubMed:27137867). Deneddylation occurs
CC upon interaction with the COP9 signalosome (CSN) complex
CC (PubMed:27137867). {ECO:0000269|PubMed:27137867}.
CC -!- SIMILARITY: Belongs to the cullin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00330}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK53839.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AC011806; AAK53839.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AY336990; AAQ01196.1; -; mRNA.
DR EMBL; AP003236; BAD61452.1; -; Genomic_DNA.
DR EMBL; AP003281; BAB64762.1; -; Genomic_DNA.
DR EMBL; AP008207; BAF04962.1; -; Genomic_DNA.
DR EMBL; AP014957; BAS72159.1; -; Genomic_DNA.
DR EMBL; CM000138; EEE54581.1; -; Genomic_DNA.
DR EMBL; AK064940; BAG89287.1; -; mRNA.
DR EMBL; AK104340; BAG96607.1; -; mRNA.
DR RefSeq; XP_015619069.1; XM_015763583.1. [Q5ZC88-1]
DR AlphaFoldDB; Q5ZC88; -.
DR SMR; Q5ZC88; -.
DR STRING; 4530.OS01T0369000-01; -.
DR PaxDb; Q5ZC88; -.
DR PRIDE; Q5ZC88; -.
DR EnsemblPlants; Os01t0369000-01; Os01t0369000-01; Os01g0369000. [Q5ZC88-1]
DR EnsemblPlants; Os01t0369000-02; Os01t0369000-02; Os01g0369000. [Q5ZC88-1]
DR GeneID; 4325735; -.
DR Gramene; Os01t0369000-01; Os01t0369000-01; Os01g0369000. [Q5ZC88-1]
DR Gramene; Os01t0369000-02; Os01t0369000-02; Os01g0369000. [Q5ZC88-1]
DR KEGG; osa:4325735; -.
DR eggNOG; KOG2166; Eukaryota.
DR HOGENOM; CLU_004747_3_0_1; -.
DR InParanoid; Q5ZC88; -.
DR OMA; GVYTAVH; -.
DR OrthoDB; 1040292at2759; -.
DR Proteomes; UP000000763; Chromosome 1.
DR Proteomes; UP000007752; Chromosome 1.
DR Proteomes; UP000059680; Chromosome 1.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; PTHR11932; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR SUPFAM; SSF74788; SSF74788; 1.
DR SUPFAM; SSF75632; SSF75632; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Reference proteome; Ubl conjugation;
KW Ubl conjugation pathway.
FT CHAIN 1..744
FT /note="Cullin-1"
FT /id="PRO_0000446886"
FT VAR_SEQ 331..342
FT /note="Missing (in isoform 2)"
FT /id="VSP_060100"
SQ SEQUENCE 744 AA; 86948 MW; F0AA32467825AD6B CRC64;
MATHERKTID LEQGWEFMQK GITKLKNILE GKPEPQFSSE DYMMLYTTIY NMCTQKPPHD
YSQQLYEKYR ESFEEYITSM VLPSLREKHD EFMLRELVKR WSNHKVMVRW LSRFFHYLDR
YFISRRSLPQ LSEVGLSCFR DLVYQEIKGK VKSAVISLID QEREGEQIDR ALLKNVLDIF
VEIGLTSMDY YENDFEDFLL KDTADYYSIK AQTWILEDSC PDYMLKAEEC LKREKERVAH
YLHSSSEQKL LEKVQHELLT QYASQLLEKE HSGCHALLRD DKVDDLSRMY RLFSRITRGL
EPVSQIFKQH VTNEGTALVK QAEDAASNKK PEKKEIVGLQ EQVFVRKIIE LHDKYVAYVT
DCFQGHTLFH KALKEAFEVF CNKGVSGSSS AELLATFCDN ILKKGGSEKL SDEAIEDTLE
KVVRLLAYIS DKDLFAEFYR KKLARRLLFD KSANDEHERS ILTKLKQQCG GQFTSKMEGM
VTDLTVARDH QAKFEEFIST HSELNPGIAL AVTVLTTGFW PSYKSFDINL PAEMVKCVEV
FKEFYQTRTK HRKLTWIYSL GTCNINAKFE AKTIELIVTT YQAALLLLFN GVDRLSYSEI
VTQLNLSDDD VVRLLHSLSC AKYKILSKEP NNRSISPNDV FEFNSKFTDK LRRLKIPLPP
VDEKKKVVED VDKDRRYAID ASIVRIMKSR KVLGHQQLVM ECVEQLGRMF KPDFKAIKKR
IEDLITRDYL ERDKDNPNVY RYLA
