ID   CUPP_BOMMO              Reviewed;         253 AA.
AC   P42852;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Pupal cuticle protein;
DE   Flags: Precursor;
GN   Name=PCP;
OS   Bombyx mori (Silk moth).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC   Bombycidae; Bombycinae; Bombyx.
OX   NCBI_TaxID=7091;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Tokai X Asahi; TISSUE=Fat body;
RA   Nakato H., Toriyama M., Izumi S., Tomino S.;
RT   "Structure and expression of mRNA for a pupal cuticle protein of the
RT   silkworm, Bombyx mori.";
RL   Insect Biochem. 20:667-678(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Tokai X Asahi; TISSUE=Fat body;
RX   PubMed=1390888; DOI=10.1016/0167-4781(92)90007-m;
RA   Nakato H., Izumi S., Tomino S.;
RT   "Structure and expression of gene coding for a pupal cuticle protein of
RT   Bombyx mori.";
RL   Biochim. Biophys. Acta 1132:161-167(1992).
CC   -!- FUNCTION: Component of the cuticle of the pupae of silk moth.
CC   -!- DEVELOPMENTAL STAGE: The level of PCP rises sharply at larval-pupal
CC       transformation.
CC   -!- DOMAIN: The tetrapeptide (A-A-P-[AV]) repeats found throughout the
CC       protein are also present in many proteins constituting the protective
CC       envelope of other species.
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DR   EMBL; X68930; CAA48756.1; -; Genomic_DNA.
DR   EMBL; X68931; CAA48756.1; JOINED; Genomic_DNA.
DR   PIR; S28943; S28943.
DR   RefSeq; NP_001119729.1; NM_001126257.2.
DR   AlphaFoldDB; P42852; -.
DR   GeneID; 100146103; -.
DR   KEGG; bmor:100146103; -.
DR   CTD; 100146103; -.
DR   InParanoid; P42852; -.
DR   OrthoDB; 1565632at2759; -.
DR   Proteomes; UP000005204; Unassembled WGS sequence.
DR   GO; GO:0042302; F:structural constituent of cuticle; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Cuticle; Reference proteome; Repeat; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..253
FT                   /note="Pupal cuticle protein"
FT                   /id="PRO_0000006403"
FT   REPEAT          97..100
FT                   /note="1"
FT   REPEAT          115..118
FT                   /note="2"
FT   REPEAT          154..157
FT                   /note="3"
FT   REGION          54..74
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          155..178
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          187..206
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        187..205
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   253 AA;  26317 MW;  963E0EA963531A0B CRC64;
     MKSMIVVACL ALACGAHASG WAGPPANIAL SQDGRNILDT PEVAQARAAH ISALQQASKN
     NPNPNDDGSY DPRWDNEEYW QQAEGKWNGA PAPAWNAAPA PSWNGAHAAA PSWNAAPAHS
     WNAAGSAPAP VAETPEVAQA RAAHLAALSA AKSAAPAQQQ WNAPAHQDWN APAHQDWNAP
     AHQDWNAPAH QSWNGAPSWQ SGAPAHQPAN IRLANDGSGI LDTPEVAAAR AAHLAAHAQA
     AHSAPAHAPQ QHW