ID   CURC_STRCN              Reviewed;         154 AA.
AC   Q02586;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Polyketide synthase CurC;
GN   Name=curC;
OS   Streptomyces cyaneus (Streptomyces curacoi).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1904;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13385 / CBS 484.68 / DSM 40107 / JCM 4219 / NBRC 12761 / NRRL
RC   B-2901 / VKM Ac-621;
RX   PubMed=1644304; DOI=10.1016/0378-1119(92)90501-f;
RA   Bergh S., Uhlen M.;
RT   "Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces
RT   curacoi.";
RL   Gene 117:131-136(1992).
CC   -!- PATHWAY: Antibiotic biosynthesis; curamycin biosynthesis.
CC   -!- SIMILARITY: Belongs to the SchB/CurC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M33704; AAA26725.1; -; Genomic_DNA.
DR   EMBL; X62518; CAA44379.1; -; Genomic_DNA.
DR   PIR; JC1212; JC1212.
DR   AlphaFoldDB; Q02586; -.
DR   SMR; Q02586; -.
DR   UniPathway; UPA00176; -.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.10; -; 1.
DR   InterPro; IPR013096; Cupin_2.
DR   InterPro; IPR016672; Polyketide_Synth_CurC_prd.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   Pfam; PF07883; Cupin_2; 1.
DR   PIRSF; PIRSF016602; CurC_prd; 1.
DR   SUPFAM; SSF51182; SSF51182; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis.
FT   CHAIN           1..154
FT                   /note="Polyketide synthase CurC"
FT                   /id="PRO_0000079562"
FT   REGION          133..154
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   154 AA;  17292 MW;  4ADE00869BB2BCB4 CRC64;
     MDKMRPRVVD VKEIEPNRKR GGDLRTLLTP VTVGATSGFM GLAIMRPGER ISEHYHPYSE
     EFVYVVEGRL EVDLDGETFP LRADQGLMIP IDMRHRFRNV GDEEARMVFH LSPLAPKPSL
     GHVDTEAPAI SDDVKAYPLV QEESGRPERP GVLS