ID   CURD_STRCN              Reviewed;         367 AA.
AC   Q02587;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Polyketide synthase CurD;
GN   Name=curD;
OS   Streptomyces cyaneus (Streptomyces curacoi).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1904;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 13385 / CBS 484.68 / DSM 40107 / JCM 4219 / NBRC 12761 / NRRL
RC   B-2901 / VKM Ac-621;
RX   PubMed=1644304; DOI=10.1016/0378-1119(92)90501-f;
RA   Bergh S., Uhlen M.;
RT   "Analysis of a polyketide synthesis-encoding gene cluster of Streptomyces
RT   curacoi.";
RL   Gene 117:131-136(1992).
CC   -!- PATHWAY: Antibiotic biosynthesis; curamycin biosynthesis.
CC   -!- SIMILARITY: Belongs to the SchA/CurD family. {ECO:0000305}.
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DR   EMBL; X62518; CAA44378.1; -; Genomic_DNA.
DR   PIR; JC1213; JC1213.
DR   AlphaFoldDB; Q02587; -.
DR   SMR; Q02587; -.
DR   UniPathway; UPA00176; -.
DR   GO; GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR007138; ABM_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR007575; SchA_CurD-like.
DR   Pfam; PF04486; SchA_CurD; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS51725; ABM; 1.
PE   3: Inferred from homology;
KW   Antibiotic biosynthesis.
FT   CHAIN           1..367
FT                   /note="Polyketide synthase CurD"
FT                   /id="PRO_0000079563"
FT   DOMAIN          15..106
FT                   /note="ABM"
SQ   SEQUENCE   367 AA;  40115 MW;  B0D1BAB31507B70F CRC64;
     MTTSPYTSQS AFDGSRMRVT LLVDPSRRRQ QEFLDAYEQM RDRVASVPDL GDQLCQSLEN
     PSQWLITSEW AAPPYLAWVN SEDHLETVKP LQSCVRDLRS MRYGIVRETG GTGPHLGGLQ
     TAVRVGDGVT RHALTFTVKP GSESKVAEVL AGYAPPQADV DDSTRLRRTT LFMHGNRVVR
     TVEVEGDLMA ALRHVARQPE VRAVEEAMNP HLEQHRDLTD PESARAFFAR AAMPAVHHVA
     RGGPEPAGLR RHALYYPARP GCGMALARLL SRQDETAAAD PAGPVTAATV FQREEIVVRL
     IDVPGDPETD PVMALGIHGK RKAAVLARLL DGAALGLAGP PTSEREATRL LTHADMTLIT
     DRRAAQP