ID   CUT19_CAEEL             Reviewed;         237 AA.
AC   H2KZ72; Q8I7F6;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2012, sequence version 1.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Cuticlin-like protein 19 {ECO:0000312|EMBL:CCD66677.1, ECO:0000312|WormBase:ZC155.5a};
DE   Flags: Precursor;
GN   Name=cutl-19;
GN   Synonyms=syx-16 {ECO:0000312|EMBL:CCD66677.1,
GN   ECO:0000312|WormBase:ZC155.5a}; ORFNames=ZC155.5;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2] {ECO:0000305}
RP   SUBCELLULAR LOCATION, INTERACTION WITH VPS-51 AND VPS-52, AND TISSUE
RP   SPECIFICITY.
RX   PubMed=21613545; DOI=10.1091/mbc.e10-06-0493;
RA   Luo L., Hannemann M., Koenig S., Hegermann J., Ailion M., Cho M.K.,
RA   Sasidharan N., Zweckstetter M., Rensing S.A., Eimer S.;
RT   "The Caenorhabditis elegans GARP complex contains the conserved Vps51
RT   subunit and is required to maintain lysosomal morphology.";
RL   Mol. Biol. Cell 22:2564-2578(2011).
CC   -!- SUBUNIT: Interacts with vps-51 and vps-52.
CC       {ECO:0000269|PubMed:21613545}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network
CC       {ECO:0000269|PubMed:21613545}.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=b {ECO:0000269|PubMed:9851916};
CC         IsoId=H2KZ72-1; Sequence=Displayed;
CC       Name=a {ECO:0000269|PubMed:9851916};
CC         IsoId=H2KZ72-2; Sequence=VSP_045746;
CC   -!- TISSUE SPECIFICITY: Expression detected in motor neurons.
CC       {ECO:0000269|PubMed:21613545}.
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DR   EMBL; FO080776; CCD66676.1; -; Genomic_DNA.
DR   EMBL; FO080776; CCD66677.1; -; Genomic_DNA.
DR   RefSeq; NP_498107.2; NM_065706.4. [H2KZ72-2]
DR   RefSeq; NP_871693.1; NM_181964.1. [H2KZ72-1]
DR   AlphaFoldDB; H2KZ72; -.
DR   SMR; H2KZ72; -.
DR   BioGRID; 55640; 4.
DR   IntAct; H2KZ72; 3.
DR   STRING; 6239.ZC155.5b; -.
DR   PaxDb; H2KZ72; -.
DR   PeptideAtlas; H2KZ72; -.
DR   EnsemblMetazoa; ZC155.5a.1; ZC155.5a.1; WBGene00022533. [H2KZ72-2]
DR   EnsemblMetazoa; ZC155.5b.1; ZC155.5b.1; WBGene00022533. [H2KZ72-1]
DR   GeneID; 191090; -.
DR   KEGG; cel:CELE_ZC155.5; -.
DR   UCSC; ZC155.5b; c. elegans.
DR   CTD; 191090; -.
DR   WormBase; ZC155.5a; CE33007; WBGene00022533; cutl-19. [H2KZ72-2]
DR   WormBase; ZC155.5b; CE33008; WBGene00022533; cutl-19. [H2KZ72-1]
DR   eggNOG; ENOG502SRI6; Eukaryota.
DR   GeneTree; ENSGT00940000163650; -.
DR   HOGENOM; CLU_1300718_0_0_1; -.
DR   InParanoid; H2KZ72; -.
DR   OMA; AMRVESC; -.
DR   OrthoDB; 1705868at2759; -.
DR   PhylomeDB; H2KZ72; -.
DR   PRO; PR:H2KZ72; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00022533; Expressed in larva and 3 other tissues.
DR   GO; GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
DR   InterPro; IPR001507; ZP_dom.
PE   1: Evidence at protein level;
KW   Alternative splicing; Golgi apparatus; Reference proteome; Signal.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..237
FT                   /note="Cuticlin-like protein 19"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000421466"
FT   VAR_SEQ         62..66
FT                   /note="Missing (in isoform a)"
FT                   /evidence="ECO:0000303|PubMed:9851916"
FT                   /id="VSP_045746"
SQ   SEQUENCE   237 AA;  27264 MW;  F4854B91B88008B7 CRC64;
     MVEYNRIFCV LVIFSTTIKC EYSELMNQKI GVRVEVLNMI YENETTITST GHPRCRLTLH
     KSGWDRDTCS SPQFKLNDTL SWSTRVCYKW VCDTTKYAMR VESCWIGSPN MSVYILRDDG
     CTIEKAILTS PVYTSFNRAA AIGWMAVRQK NMKYMHVGCT IRLCHLCDPK CQTITPPRTC
     NDNRADDYEA MWNSSSRVKN LCFPEPSTTE NLNLNFGNSP FQNVGNIIIL LLVFLLR