CUTA_ARCFU
ID CUTA_ARCFU Reviewed; 102 AA.
AC O28301;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 105.
DE RecName: Full=Divalent-cation tolerance protein CutA;
GN Name=cutA; OrderedLocusNames=AF_1978;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS).
RA Kniewel R., Buglino J.A., Lima C.D.;
RT "Structure of the periplasmic divalent cation tolerance protein CutA from
RT Archaeoglobus fulgidus.";
RL Submitted (APR-2003) to the PDB data bank.
CC -!- FUNCTION: Involved in resistance toward heavy metals. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CutA family. {ECO:0000305}.
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DR EMBL; AE000782; AAB89277.1; -; Genomic_DNA.
DR PIR; A69497; A69497.
DR RefSeq; WP_010879470.1; NC_000917.1.
DR PDB; 1P1L; X-ray; 2.00 A; A=1-102.
DR PDBsum; 1P1L; -.
DR AlphaFoldDB; O28301; -.
DR SMR; O28301; -.
DR STRING; 224325.AF_1978; -.
DR EnsemblBacteria; AAB89277; AAB89277; AF_1978.
DR GeneID; 24795721; -.
DR KEGG; afu:AF_1978; -.
DR eggNOG; arCOG04231; Archaea.
DR HOGENOM; CLU_098807_3_1_2; -.
DR OMA; VYTTFPD; -.
DR OrthoDB; 110178at2157; -.
DR PhylomeDB; O28301; -.
DR EvolutionaryTrace; O28301; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0010038; P:response to metal ion; IEA:InterPro.
DR Gene3D; 3.30.70.120; -; 1.
DR InterPro; IPR004323; Ion_tolerance_CutA.
DR InterPro; IPR011322; N-reg_PII-like_a/b.
DR InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR PANTHER; PTHR23419; PTHR23419; 1.
DR Pfam; PF03091; CutA1; 1.
DR SUPFAM; SSF54913; SSF54913; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..102
FT /note="Divalent-cation tolerance protein CutA"
FT /id="PRO_0000157128"
FT STRAND 2..11
FT /evidence="ECO:0007829|PDB:1P1L"
FT HELIX 12..24
FT /evidence="ECO:0007829|PDB:1P1L"
FT STRAND 29..42
FT /evidence="ECO:0007829|PDB:1P1L"
FT STRAND 45..59
FT /evidence="ECO:0007829|PDB:1P1L"
FT HELIX 60..62
FT /evidence="ECO:0007829|PDB:1P1L"
FT HELIX 63..73
FT /evidence="ECO:0007829|PDB:1P1L"
FT STRAND 75..78
FT /evidence="ECO:0007829|PDB:1P1L"
FT STRAND 81..85
FT /evidence="ECO:0007829|PDB:1P1L"
FT HELIX 91..101
FT /evidence="ECO:0007829|PDB:1P1L"
SQ SEQUENCE 102 AA; 11885 MW; F66D8291841A0689 CRC64;
MHNFIYITAP SLEEAERIAK RLLEKKLAAC VNIFPIKSFF WWEGKIEAAT EFAMIVKTRS
EKFAEVRDEV KAMHSYTTPC ICAIPIERGL KEFLDWIDET VE
