ID   CUTA_CRYPI              Reviewed;         117 AA.
AC   Q5CX58;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2012, sequence version 2.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Divalent-cation tolerance protein cutA homolog;
GN   ORFNames=cgd6_2410;
OS   Cryptosporidium parvum (strain Iowa II).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=353152;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Iowa II;
RX   PubMed=15044751; DOI=10.1126/science.1094786;
RA   Abrahamsen M.S., Templeton T.J., Enomoto S., Abrahante J.E., Zhu G.,
RA   Lancto C.A., Deng M., Liu C., Widmer G., Tzipori S., Buck G.A., Xu P.,
RA   Bankier A.T., Dear P.H., Konfortov B.A., Spriggs H.F., Iyer L.,
RA   Anantharaman V., Aravind L., Kapur V.;
RT   "Complete genome sequence of the apicomplexan, Cryptosporidium parvum.";
RL   Science 304:441-445(2004).
CC   -!- SUBUNIT: Homotrimer. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CutA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EAK90138.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AAEE01000002; EAK90138.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_627596.1; XM_627596.1.
DR   PDB; 4E98; X-ray; 2.00 A; A/B/C=2-117.
DR   PDBsum; 4E98; -.
DR   AlphaFoldDB; Q5CX58; -.
DR   SMR; Q5CX58; -.
DR   STRING; 353152.Q5CX58; -.
DR   EnsemblProtists; EAK90138; EAK90138; cgd6_2410.
DR   GeneID; 3375883; -.
DR   KEGG; cpv:cgd6_2410; -.
DR   InParanoid; Q5CX58; -.
DR   Proteomes; UP000006726; Chromosome 6.
DR   GO; GO:0010038; P:response to metal ion; IEA:InterPro.
DR   Gene3D; 3.30.70.120; -; 1.
DR   InterPro; IPR004323; Ion_tolerance_CutA.
DR   InterPro; IPR011322; N-reg_PII-like_a/b.
DR   InterPro; IPR015867; N-reg_PII/ATP_PRibTrfase_C.
DR   PANTHER; PTHR23419; PTHR23419; 1.
DR   Pfam; PF03091; CutA1; 1.
DR   SUPFAM; SSF54913; SSF54913; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Reference proteome.
FT   CHAIN           1..117
FT                   /note="Divalent-cation tolerance protein cutA homolog"
FT                   /id="PRO_0000417424"
FT   STRAND          15..24
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   HELIX           25..37
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   STRAND          42..56
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   STRAND          59..73
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   HELIX           74..76
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   HELIX           77..87
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   STRAND          89..92
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   STRAND          95..99
FT                   /evidence="ECO:0007829|PDB:4E98"
FT   HELIX           105..114
FT                   /evidence="ECO:0007829|PDB:4E98"
SQ   SEQUENCE   117 AA;  13284 MW;  65E0B7E17DDC3AF9 CRC64;
     MINSNMTETK IESNIILIYI SAPNQDEATS IAKTLVDEEL CACVSIIPSV RSIYKFKGQV
     HDENEVMLLV KTTSQLFTTL KEKVTEIHSY ELPEIIATKV VYGNENYINW VNQTVRS