CVC1_EHV1B
ID CVC1_EHV1B Reviewed; 706 AA.
AC P28950; Q6DLG5;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Capsid vertex component 1 {ECO:0000255|HAMAP-Rule:MF_04017};
GN Name=CVC1 {ECO:0000255|HAMAP-Rule:MF_04017}; OrderedLocusNames=45;
OS Equine herpesvirus 1 (strain Ab4p) (EHV-1) (Equine abortion virus).
OC Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC Herpesvirales; Herpesviridae; Alphaherpesvirinae; Varicellovirus.
OX NCBI_TaxID=31520;
OH NCBI_TaxID=9796; Equus caballus (Horse).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=1318606; DOI=10.1016/0042-6822(92)90706-u;
RA Telford E.A.R., Watson M.S., McBride K., Davison A.J.;
RT "The DNA sequence of equine herpesvirus-1.";
RL Virology 189:304-316(1992).
CC -!- FUNCTION: Capsid vertex-specific component that plays a role during
CC viral DNA encapsidation, assuring correct genome cleavage and
CC presumably stabilizing capsids that contain full-length viral genomes.
CC {ECO:0000255|HAMAP-Rule:MF_04017}.
CC -!- SUBUNIT: Interacts (via C-terminus) with capsid vertex component
CC 2/CVC2. {ECO:0000255|HAMAP-Rule:MF_04017}.
CC -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04017}. Host
CC nucleus {ECO:0000255|HAMAP-Rule:MF_04017}.
CC -!- SIMILARITY: Belongs to the herpesviridae CVC1 protein family.
CC {ECO:0000255|HAMAP-Rule:MF_04017}.
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DR EMBL; AY665713; AAT67303.1; -; Genomic_DNA.
DR PIR; A36800; WZBED8.
DR RefSeq; YP_053091.1; NC_001491.2.
DR SMR; P28950; -.
DR GeneID; 1487537; -.
DR KEGG; vg:1487537; -.
DR Proteomes; UP000001189; Genome.
DR GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR HAMAP; MF_04017; HSV_CVC1; 1.
DR InterPro; IPR007640; UL17-like.
DR Pfam; PF04559; Herpes_UL17; 1.
PE 3: Inferred from homology;
KW Capsid protein; Host nucleus; Late protein; Reference proteome;
KW Viral genome packaging; Viral release from host cell; Virion.
FT CHAIN 1..706
FT /note="Capsid vertex component 1"
FT /id="PRO_0000115961"
FT REGION 321..347
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 706 AA; 76321 MW; 10C7DDEF62D3270C CRC64;
MDAHIANETK HLLVHGNSKT RALVHIIVPD ACLKKAGVDP VKLSDRHRAS PSAAPVFRVF
AQTRYHATGE CSLWRTVFAG YVPSGAIVSA LVPTVPADHP RLFQSTPDSG GLFVSLEIEC
DADGRFDAFT LVALRVDIAD DPRTTEVLFT YDELLPPGTR YGADSKRVAL LCRQFVAYVN
SHPTVSQSAV TAASHIEAAV AEDVKSASGP QVSYGARIDP AEYLFSGGGF DNHQALARLE
DDDKEIMSLI RRASEVIAKR NPVRVLSNPE VNGDAHRRQC VASGLRQGAR GAHASDSHAR
VGFNSSIHDA TALLLGLEPP DSGRFVNSGP QRHLPPQGPR SPASRDCQSG MLDDVLLLTP
ENSNPLTPLD WLDVGHAAVA GGDTPRDVWR RRPISLVARK HYGTCETFVV VSYENSTAWG
GRRARDEHLA GSINPPVMQA CVAAGVDHPR NLPPETRGEL IAKFPMLTVP LGDTPPPVAA
FDAAAELALI DHFRGACVSA LLKAISERLR AEPRMSQLIE YDIPNNNRDC IISVAQRAPE
LLEAVALAIQ NVTVTEFCNS ALMLSALSHL NILSGNKRGR LPYHRSWLPS LAGGADAFLF
DYYSSGGEVV KVSPVPLAIL VTATRTGQHS CRFARGAPDS SSKTYERYLP GECYAYICVG
LNRSFEALVV LPGGFACRAS AARKLAWPAH LVEPILERYC WTIPSH