ID   CVC1_EHV2               Reviewed;         478 AA.
AC   Q66635;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-NOV-2015, sequence version 2.
DT   03-AUG-2022, entry version 61.
DE   RecName: Full=Capsid vertex component 1 {ECO:0000255|HAMAP-Rule:MF_04017};
GN   Name=CVC1 {ECO:0000255|HAMAP-Rule:MF_04017}; OrderedLocusNames=32;
OS   Equine herpesvirus 2 (strain 86/87) (EHV-2).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Gammaherpesvirinae; Percavirus.
OX   NCBI_TaxID=82831;
OH   NCBI_TaxID=9796; Equus caballus (Horse).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=7783207; DOI=10.1006/jmbi.1995.0314;
RA   Telford E.A.R., Watson M.S., Aird H.C., Perry J., Davison A.J.;
RT   "The DNA sequence of equine herpesvirus 2.";
RL   J. Mol. Biol. 249:520-528(1995).
RN   [2]
RP   SEQUENCE REVISION.
RA   Davison A.J.;
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Capsid vertex-specific component that plays a role during
CC       viral DNA encapsidation, assuring correct genome cleavage and
CC       presumably stabilizing capsids that contain full-length viral genomes.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBUNIT: Interacts (via C-terminus) with capsid vertex component
CC       2/CVC2. {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04017}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SIMILARITY: Belongs to the herpesviridae CVC1 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
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DR   EMBL; U20824; AAC13819.2; -; Genomic_DNA.
DR   PIR; S55626; S55626.
DR   RefSeq; NP_042628.2; NC_001650.2.
DR   SMR; Q66635; -.
DR   GeneID; 1461066; -.
DR   KEGG; vg:1461066; -.
DR   Proteomes; UP000007083; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04017; HSV_CVC1; 1.
DR   InterPro; IPR007640; UL17-like.
DR   Pfam; PF04559; Herpes_UL17; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Late protein; Reference proteome;
KW   Viral genome packaging; Viral release from host cell; Virion.
FT   CHAIN           1..478
FT                   /note="Capsid vertex component 1"
FT                   /id="PRO_0000406063"
FT   REGION          131..184
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        136..159
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   478 AA;  51568 MW;  AE57403E45CB5574 CRC64;
     MDVHLGNWRL CGRRCGRLAH VVLPEAFLDR HGLAEDAGAE FFVQTRFTGS LRPSSYVRVI
     GAFFGGGSGD EIARRDRRSA LNLVLSLPLL ADGDGRYDPH NIATLKVRSG DGRRLVFVDF
     FYLSLLGAQM PRGPESEGEG GKDGGAGRGD GEASRESPLE RIAAEASGPG PGSGRGRSAG
     GRRASPLSVL SGLLDNKYTQ IAKHHRALED PGAVRGVNIE PDRRDHGNLA GVGKRKVRCA
     LNLIDLKRDD ITFTSSTHLL SGTRFTLCHY PRPVAPPGGA PWESTLDGLS ERQLRGVDPL
     AALILGFDFL ERAQTGLVNS LARECENGGL KIFQRLPVCV EKKHDIRGVL GDHFTEACHV
     LARQVGESCA WVRACVSGER GHVGLWADFL NLWEAGPSTL GVDLSYLFSP GPPDDESAFW
     ARLLGSDRLL DAIKTGARAV LVVDSQLAAW LLLPGGFAIK GRYSLSREDI QITVGRYG