ID   CVC1_GAHVM              Reviewed;         729 AA.
AC   Q9E6Q0;
DT   05-APR-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 64.
DE   RecName: Full=Capsid vertex component 1 {ECO:0000255|HAMAP-Rule:MF_04017};
GN   Name=CVC1 {ECO:0000255|HAMAP-Rule:MF_04017}; OrderedLocusNames=MDV029;
OS   Gallid herpesvirus 2 (strain Chicken/Md5/ATCC VR-987) (GaHV-2) (Marek's
OS   disease herpesvirus type 1).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Alphaherpesvirinae; Mardivirus.
OX   NCBI_TaxID=10389;
OH   NCBI_TaxID=9031; Gallus gallus (Chicken).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10933706; DOI=10.1128/jvi.74.17.7980-7988.2000;
RA   Tulman E.R., Afonso C.L., Lu Z., Zsak L., Rock D.L., Kutish G.F.;
RT   "The genome of a very virulent Marek's disease virus.";
RL   J. Virol. 74:7980-7988(2000).
CC   -!- FUNCTION: Capsid vertex-specific component that plays a role during
CC       viral DNA encapsidation, assuring correct genome cleavage and
CC       presumably stabilizing capsids that contain full-length viral genomes.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBUNIT: Interacts (via C-terminus) with capsid vertex component
CC       2/CVC2. {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04017}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SIMILARITY: Belongs to the herpesviridae CVC1 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
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DR   EMBL; AF243438; AAG14209.1; -; Genomic_DNA.
DR   RefSeq; YP_001033945.1; NC_002229.3.
DR   SMR; Q9E6Q0; -.
DR   GeneID; 4811490; -.
DR   KEGG; vg:4811490; -.
DR   Proteomes; UP000008072; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04017; HSV_CVC1; 1.
DR   InterPro; IPR007640; UL17-like.
DR   Pfam; PF04559; Herpes_UL17; 1.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Late protein; Reference proteome;
KW   Viral genome packaging; Viral release from host cell; Virion.
FT   CHAIN           1..729
FT                   /note="Capsid vertex component 1"
FT                   /id="PRO_0000406545"
SQ   SEQUENCE   729 AA;  80917 MW;  AB47D99030AE9D2D CRC64;
     MEAHIESETI YSLSNFDRGA MRHLLTHIII PDECLSAAGI DLTNLKDASP RYTTSVYSSL
     SVSVGVQIRQ NATGLCSNWS NVYGEYVPSG ALHSLLVPQV TNPAVFSTSN QSDQGALFIS
     LPIECDSQNR FDPFTSVALR IPCSDIRTGD YKSYKDILFT QDELVPIGTR YNNDTERLQT
     LFLQFLQYTK KFESELPVTI IELGAKLEAC IGNVDDVIHS QSKQFDIMHL LANNKHEFDT
     PDIAARIEAD NTEIVQLIKK AAEAITKRAP VSGSLEKGSL GVVSGLKQGA IACLKNNTDL
     PSKNTQQKAV MNGLEPAGKI RFVGDGNTNV RLSSAMNHQL KEITTNFEDV LMFDSPSQKP
     VDSKEIFLTA IGILGNGITL ANLWRCGSIS IVTRVHSTTK SQFYIVAYEN SVALGGRSSH
     LTPNPTSLNI LLSIACQEEG VDHPCYLSQE RKIDIARQAP ILSDPLLREH NQLQAFSAGS
     EIDLMIDFKT HISNCVISAI GEALRMEPNL YQMISYHIHA YDLPFITEIT NRTPNYIRAT
     LNAISNSSWE KFSTGALISA AISYMAGYIN KFGGKAYRRY TTENAAEHLG GDYQLVNTKI
     PGLVLFDYYS TGGECIKLNN RPVPIILNGG VDLWNRQPYN RSVMTCTFPE WFVPHATCEK
     FLPGESYAYI CVGYDEHLHI AIVLPAGFML TAHTEFNWPV ARIEAVLSRL CRTNKMQQVL
     RPYVSEVYM