ID   CVC1_HHV6Z              Reviewed;         442 AA.
AC   Q9QJ20;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Capsid vertex component 1 {ECO:0000255|HAMAP-Rule:MF_04017};
GN   Name=CVC1 {ECO:0000255|HAMAP-Rule:MF_04017}; OrderedLocusNames=U64;
OS   Human herpesvirus 6B (strain Z29) (HHV-6 variant B) (Human B lymphotropic
OS   virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=36351;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10482553; DOI=10.1128/jvi.73.10.8040-8052.1999;
RA   Dominguez G., Dambaugh T.R., Stamey F.R., Dewhurst S., Inoue N.,
RA   Pellett P.E.;
RT   "Human herpesvirus 6B genome sequence: coding content and comparison with
RT   human herpesvirus 6A.";
RL   J. Virol. 73:8040-8052(1999).
CC   -!- FUNCTION: Capsid vertex-specific component that plays a role during
CC       viral DNA encapsidation, assuring correct genome cleavage and
CC       presumably stabilizing capsids that contain full-length viral genomes.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBUNIT: Interacts (via C-terminus) with capsid vertex component
CC       2/CVC2. {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04017}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SIMILARITY: Belongs to the herpesviridae CVC1 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
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DR   EMBL; AF157706; AAD49665.1; -; Genomic_DNA.
DR   RefSeq; NP_050244.1; NC_000898.1.
DR   SMR; Q9QJ20; -.
DR   PRIDE; Q9QJ20; -.
DR   DNASU; 1497064; -.
DR   GeneID; 1497064; -.
DR   KEGG; vg:1497064; -.
DR   Proteomes; UP000006930; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04017; HSV_CVC1; 1.
DR   InterPro; IPR007640; UL17-like.
DR   Pfam; PF04559; Herpes_UL17; 2.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Late protein; Reference proteome;
KW   Viral genome packaging; Viral release from host cell; Virion.
FT   CHAIN           1..442
FT                   /note="Capsid vertex component 1"
FT                   /id="PRO_0000408434"
SQ   SEQUENCE   442 AA;  51636 MW;  3625A9CFAB0C012E CRC64;
     METHLYYDTL YQYQGGVYPA HICLPTDAYL PMRVDCIESL YFRCVFFKNG MHYTEWSKLK
     FTVISREIKF KDVLKNADFD ELFTGLVVMT IPIPIVDFHF DIDSVILKLV YPQLVHREIV
     LRLYDLICIR PSSDRPSEVS AKNIGIDFYQ LTSQGNKQTP DEEKRCLFFQ QGPLEPPSTV
     RGLKAAGNAK PMQFPAHVNE KMTESFLSDS WFEQKVRCKK ILDFTQTYRV VVCWYELSFS
     REMQIENNLL SASQLKRVNA ADFWDRTDRY LRDIGSRVLT HIVKTLQIHN RQFKQKFNCN
     FPVNFSFEHL LSFMQLGKDF WILNLTLDSC IIKAIICFLG FRNGRKSFLA QDEVWGDLID
     CSKGSVIYGE KIQWILDSTN NLYSTRREKQ NKSWELYVDC CALYVSEKLE LDFVLPGGFA
     ITGKFALTDG DIDFFNWRFG LS