ID   CVC1_HHV7J              Reviewed;         439 AA.
AC   P52360;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Capsid vertex component 1 {ECO:0000255|HAMAP-Rule:MF_04017};
GN   Name=CVC1 {ECO:0000255|HAMAP-Rule:MF_04017}; OrderedLocusNames=U64;
OS   Human herpesvirus 7 (strain JI) (HHV-7) (Human T lymphotropic virus).
OC   Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes;
OC   Herpesvirales; Herpesviridae; Betaherpesvirinae; Roseolovirus.
OX   NCBI_TaxID=57278;
OH   NCBI_TaxID=9606; Homo sapiens (Human).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=8709220; DOI=10.1128/jvi.70.9.5975-5989.1996;
RA   Nicholas J.;
RT   "Determination and analysis of the complete nucleotide sequence of human
RT   herpesvirus.";
RL   J. Virol. 70:5975-5989(1996).
CC   -!- FUNCTION: Capsid vertex-specific component that plays a role during
CC       viral DNA encapsidation, assuring correct genome cleavage and
CC       presumably stabilizing capsids that contain full-length viral genomes.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBUNIT: Interacts (via C-terminus) with capsid vertex component
CC       2/CVC2. {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000255|HAMAP-Rule:MF_04017}. Host
CC       nucleus {ECO:0000255|HAMAP-Rule:MF_04017}.
CC   -!- SIMILARITY: Belongs to the herpesviridae CVC1 protein family.
CC       {ECO:0000255|HAMAP-Rule:MF_04017}.
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DR   EMBL; U43400; AAC54726.1; -; Genomic_DNA.
DR   PIR; T41966; T41966.
DR   SMR; P52360; -.
DR   Proteomes; UP000009246; Genome.
DR   GO; GO:0042025; C:host cell nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0019028; C:viral capsid; IEA:UniProtKB-UniRule.
DR   GO; GO:0051276; P:chromosome organization; IEA:InterPro.
DR   GO; GO:0019076; P:viral release from host cell; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_04017; HSV_CVC1; 1.
DR   InterPro; IPR007640; UL17-like.
DR   Pfam; PF04559; Herpes_UL17; 2.
PE   3: Inferred from homology;
KW   Capsid protein; Host nucleus; Late protein; Reference proteome;
KW   Viral genome packaging; Viral release from host cell; Virion.
FT   CHAIN           1..439
FT                   /note="Capsid vertex component 1"
FT                   /id="PRO_0000115960"
SQ   SEQUENCE   439 AA;  51355 MW;  73121429DFD37194 CRC64;
     MEMHLLCETM FTCRKNNILP VHLCILLDDV IHKEKVKAIE GIFFQCVFFK EKLVYTEWTK
     IKFTYVLHDL VISQIFKNAC IKEVIHGALI LSVPINIDNL HFDTDILILK IIYPHFLHDD
     IVIKLSEILS GAPRMQKTVE KKQEVEKPFF HIPAKLGDLT KEDPISFNHH GPLEPPSTVR
     GLKQSANVRH SHPISRPEKA NVTFLSDSWY SQNLKCDFIS DIQQRHVLVI FWYELSKGIQ
     MQIKNIQIPP ENLFSSITNY LDRVNTYLDE IAERTFRCIT TNMEIQNRHL PQKFNSHFQI
     EFNCTHLISG MELARDFWIL SLDRNSCVLK AMASHFLHKK KGRSSLSSNE FWADLIDCTT
     GKTLYGEKVR WQLNSETSLY STFRKNQNIS WELQPNCYAL YMSENLKLYW VLPGGFCVSG
     TFKLKENDEF FFDWQFGMS