ID   CVF1_CONPO              Reviewed;          75 AA.
AC   B3FIA6;
DT   02-MAR-2010, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 1.
DT   25-MAY-2022, entry version 22.
DE   RecName: Full=Conotoxin Vt15.1;
DE   Flags: Precursor;
OS   Conus planorbis (Planorbis cone).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Caenogastropoda; Neogastropoda; Conoidea; Conidae; Conus; Strategoconus.
OX   NCBI_TaxID=97183;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom duct;
RX   PubMed=18304695; DOI=10.1016/j.peptides.2008.01.007;
RA   Peng C., Liu L., Shao X.X., Chi C.-W., Wang C.G.;
RT   "Identification of a novel class of conotoxins defined as V-conotoxins with
RT   a unique cysteine pattern and signal peptide sequence.";
RL   Peptides 29:985-991(2008).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC   -!- DOMAIN: The cysteine framework is XV (C-C-CC-C-C-C-C).
CC   -!- PTM: Contains 4 disulfide bonds. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the conotoxin V superfamily. {ECO:0000305}.
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DR   EMBL; EU169207; ABY26940.1; -; mRNA.
DR   AlphaFoldDB; B3FIA6; -.
DR   SMR; B3FIA6; -.
DR   ConoServer; 2787; Vt15.1 precursor.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Amidation; Cleavage on pair of basic residues; Disulfide bond; Secreted;
KW   Signal; Toxin.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   PROPEP          20..43
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000392198"
FT   PEPTIDE         46..73
FT                   /note="Conotoxin Vt15.1"
FT                   /id="PRO_0000392199"
FT   MOD_RES         73
FT                   /note="Tryptophan amide"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   75 AA;  8298 MW;  AF0A88D79EDC08B9 CRC64;
     MMPVILPLLL SLAIRGGDGQ AIQGDRDLIA KLFKRYQEHG LSVKRACHTC DDGTECCDSR
     CSCPWNTCTC IPWGK