ID   CVFB_STAA3              Reviewed;         300 AA.
AC   Q2FH47;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Conserved virulence factor B;
GN   Name=cvfB; OrderedLocusNames=SAUSA300_1284;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- FUNCTION: Contributes to the expression of virulence factors and to
CC       pathogenicity. Involved in the production of hemolysin, DNase, protease
CC       and protein A (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CvfB family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD22747.1; -; Genomic_DNA.
DR   RefSeq; WP_001162359.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FH47; -.
DR   SMR; Q2FH47; -.
DR   EnsemblBacteria; ABD22747; ABD22747; SAUSA300_1284.
DR   KEGG; saa:SAUSA300_1284; -.
DR   HOGENOM; CLU_064885_0_0_9; -.
DR   OMA; GAFMDWG; -.
DR   Proteomes; UP000001939; Chromosome.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 2.40.50.140; -; 2.
DR   InterPro; IPR014464; CvfB_fam.
DR   InterPro; IPR039566; CvfB_S1.
DR   InterPro; IPR040764; CvfB_WH.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR37296; PTHR37296; 1.
DR   Pfam; PF17783; CvfB_WH; 1.
DR   Pfam; PF13509; S1_2; 1.
DR   PIRSF; PIRSF012524; YitL_S1; 1.
PE   3: Inferred from homology;
KW   Virulence.
FT   CHAIN           1..300
FT                   /note="Conserved virulence factor B"
FT                   /id="PRO_0000282297"
SQ   SEQUENCE   300 AA;  34199 MW;  690F0A4784BA9D0C CRC64;
     MALDKDIVGS IEFLEVVGLQ GSTYLLKGPN GENVKLNQSE MNDDDELEVG EEYSFFIYPN
     RSGELFATQN MPDITKDKYD FAKVLKTDRD GARIDVGLPR EVLVPWEDLP KVKSLWPQPG
     DYLLVTLRID RENHMYGRLA SESVVENMFT PVHDDNLKNE VIEAKPYRVL RIGSFLLSES
     GYKIFVHESE RKAEPRLGES VQVRIIGHND KGELNGSFLP LAHERLDDDG QVIFDLLVEY
     DGELPFWDKS SPEAIKEVFN MSKGSFKRAI GHLYKQKIIN IETGKIALTK KGWSRMDSKE