ID   CVFC_STAA3              Reviewed;         374 AA.
AC   Q2FH09;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   21-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Conserved virulence factor C;
GN   Name=cvfC; OrderedLocusNames=SAUSA300_1322;
OS   Staphylococcus aureus (strain USA300).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=367830;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USA300;
RX   PubMed=16517273; DOI=10.1016/s0140-6736(06)68231-7;
RA   Diep B.A., Gill S.R., Chang R.F., Phan T.H., Chen J.H., Davidson M.G.,
RA   Lin F., Lin J., Carleton H.A., Mongodin E.F., Sensabaugh G.F.,
RA   Perdreau-Remington F.;
RT   "Complete genome sequence of USA300, an epidemic clone of community-
RT   acquired meticillin-resistant Staphylococcus aureus.";
RL   Lancet 367:731-739(2006).
CC   -!- FUNCTION: Required for hemolysin production. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CvfC family. {ECO:0000305}.
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DR   EMBL; CP000255; ABD21983.1; -; Genomic_DNA.
DR   RefSeq; WP_000404653.1; NZ_CP027476.1.
DR   AlphaFoldDB; Q2FH09; -.
DR   SMR; Q2FH09; -.
DR   EnsemblBacteria; ABD21983; ABD21983; SAUSA300_1322.
DR   KEGG; saa:SAUSA300_1322; -.
DR   HOGENOM; CLU_733295_0_0_9; -.
DR   OMA; VKGVYHV; -.
DR   Proteomes; UP000001939; Chromosome.
DR   Gene3D; 1.25.10.10; -; 1.
DR   Gene3D; 3.30.1370.70; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014824; Nfu/NifU_N.
DR   InterPro; IPR036498; Nfu/NifU_N_sf.
DR   InterPro; IPR004155; PBS_lyase_HEAT.
DR   InterPro; IPR025989; Virulence_F_dom.
DR   Pfam; PF08712; Nfu_N; 1.
DR   Pfam; PF13769; Virulence_fact; 1.
DR   SMART; SM00567; EZ_HEAT; 3.
DR   SMART; SM00932; Nfu_N; 1.
DR   SUPFAM; SSF110836; SSF110836; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Virulence.
FT   CHAIN           1..374
FT                   /note="Conserved virulence factor C"
FT                   /id="PRO_0000282310"
SQ   SEQUENCE   374 AA;  42981 MW;  CAB61D639EF0E5D1 CRC64;
     MEILRIEPTP SPNTMKVVLS YTREDKLSNT YKKVEETQPR FINQLLSIDG ITSIFHVMNF
     LAVDKAPKAD WEVILPDIKA AFSDANKVLE SVNEPQIDNH FGEIKAELLT FKGIPYQIKL
     TSADQELREQ LPQTYVDHMT QAQTAHDNIV FMRKWLDLGN RYGNIQEVMD GVLEEVLTTY
     PESQLPVLVK HALEENHATN NYHFYRHVSL DEYHATDNWK TRLRMLNHFP KPTFEDIPLL
     DLALSDEKVP VRRQAIVLLG MIESKEILPY LYKGLRDKSP VVRRTAGDCI SDLGYPEALP
     EMVLLLDDPQ KIVRWRAAMF IFDEGNAEQL PALKAHINDN AFEVKLQIEM AISRIENGDE
     ALGSVWKQMA NRTI