ID   CVFC_STAAB              Reviewed;         374 AA.
AC   Q2YY38;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   25-MAY-2022, entry version 89.
DE   RecName: Full=Conserved virulence factor C;
GN   Name=cvfC; OrderedLocusNames=SAB1284c;
OS   Staphylococcus aureus (strain bovine RF122 / ET3-1).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=273036;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=bovine RF122 / ET3-1;
RX   PubMed=17971880; DOI=10.1371/journal.pone.0001120;
RA   Herron-Olson L., Fitzgerald J.R., Musser J.M., Kapur V.;
RT   "Molecular correlates of host specialization in Staphylococcus aureus.";
RL   PLoS ONE 2:E1120-E1120(2007).
CC   -!- FUNCTION: Required for hemolysin production. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CvfC family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AJ938182; CAI80973.1; -; Genomic_DNA.
DR   RefSeq; WP_000404637.1; NC_007622.1.
DR   AlphaFoldDB; Q2YY38; -.
DR   SMR; Q2YY38; -.
DR   KEGG; sab:SAB1284c; -.
DR   HOGENOM; CLU_733295_0_0_9; -.
DR   OMA; VKGVYHV; -.
DR   Gene3D; 1.25.10.10; -; 1.
DR   Gene3D; 3.30.1370.70; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014824; Nfu/NifU_N.
DR   InterPro; IPR036498; Nfu/NifU_N_sf.
DR   InterPro; IPR004155; PBS_lyase_HEAT.
DR   InterPro; IPR025989; Virulence_F_dom.
DR   Pfam; PF08712; Nfu_N; 1.
DR   Pfam; PF13769; Virulence_fact; 1.
DR   SMART; SM00567; EZ_HEAT; 3.
DR   SMART; SM00932; Nfu_N; 1.
DR   SUPFAM; SSF110836; SSF110836; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Virulence.
FT   CHAIN           1..374
FT                   /note="Conserved virulence factor C"
FT                   /id="PRO_0000282302"
SQ   SEQUENCE   374 AA;  42874 MW;  FF1A179D4B06BAB7 CRC64;
     MEILRIEPTP SPNTMKVVLS YTREDKLSNT YKKVEETQPE FINQLLSIDG ITSIFHVMNF
     LAVDKSPKAD WEVILPDIKA AFSDANKVLE SVNEPQIDNH FGEIKAELLT FKGIPYQIKL
     TSADQELREQ LPQTYVDQMT QAQTAHDNIV FMRKWLDLGN RYGNIEEVMD GVLEEVLATY
     PESQLPVLVK HALEENHATN NYHFYRHVSL DEYHATDNWK TRLRTLNHFP KPTFEDIPLL
     DLALSDEKVP VRRQAIVLLG MIESKEILPY LYKGLRDKSP AVRRTAGDCI SDLGYPEALP
     EMVLLLDDPQ KIVRWRAAMF IFDEGNAEQL PALKAHINDN AFEVKLQIEM AISRIENGDE
     ALGSVWKQMA NRTI