CVFC_STAAM
ID CVFC_STAAM Reviewed; 374 AA.
AC Q931R7;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Conserved virulence factor C;
GN Name=cvfC; OrderedLocusNames=SAV1429;
OS Staphylococcus aureus (strain Mu50 / ATCC 700699).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=158878;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mu50 / ATCC 700699;
RX PubMed=11418146; DOI=10.1016/s0140-6736(00)04403-2;
RA Kuroda M., Ohta T., Uchiyama I., Baba T., Yuzawa H., Kobayashi I., Cui L.,
RA Oguchi A., Aoki K., Nagai Y., Lian J.-Q., Ito T., Kanamori M.,
RA Matsumaru H., Maruyama A., Murakami H., Hosoyama A., Mizutani-Ui Y.,
RA Takahashi N.K., Sawano T., Inoue R., Kaito C., Sekimizu K., Hirakawa H.,
RA Kuhara S., Goto S., Yabuzaki J., Kanehisa M., Yamashita A., Oshima K.,
RA Furuya K., Yoshino C., Shiba T., Hattori M., Ogasawara N., Hayashi H.,
RA Hiramatsu K.;
RT "Whole genome sequencing of meticillin-resistant Staphylococcus aureus.";
RL Lancet 357:1225-1240(2001).
CC -!- FUNCTION: Required for hemolysin production. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the CvfC family. {ECO:0000305}.
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DR EMBL; BA000017; BAB57591.1; -; Genomic_DNA.
DR RefSeq; WP_000404649.1; NC_002758.2.
DR AlphaFoldDB; Q931R7; -.
DR SMR; Q931R7; -.
DR World-2DPAGE; 0002:Q931R7; -.
DR PaxDb; Q931R7; -.
DR DNASU; 1121404; -.
DR EnsemblBacteria; BAB57591; BAB57591; SAV1429.
DR KEGG; sav:SAV1429; -.
DR HOGENOM; CLU_733295_0_0_9; -.
DR OMA; VKGVYHV; -.
DR PhylomeDB; Q931R7; -.
DR BioCyc; SAUR158878:SAV_RS07700-MON; -.
DR Proteomes; UP000002481; Chromosome.
DR Gene3D; 1.25.10.10; -; 1.
DR Gene3D; 3.30.1370.70; -; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014824; Nfu/NifU_N.
DR InterPro; IPR036498; Nfu/NifU_N_sf.
DR InterPro; IPR004155; PBS_lyase_HEAT.
DR InterPro; IPR025989; Virulence_F_dom.
DR Pfam; PF08712; Nfu_N; 1.
DR Pfam; PF13769; Virulence_fact; 1.
DR SMART; SM00567; EZ_HEAT; 3.
DR SMART; SM00932; Nfu_N; 1.
DR SUPFAM; SSF110836; SSF110836; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 3: Inferred from homology;
KW Virulence.
FT CHAIN 1..374
FT /note="Conserved virulence factor C"
FT /id="PRO_0000282306"
SQ SEQUENCE 374 AA; 42972 MW; 192313D3B75C7FA3 CRC64;
MEILRIEPTP SPNTMKVVLS YTREDKLSNT YKKVEETQPR FINQLLSIDG ITSIFHVMNF
LAVDKAPKAD WEVILPDIKA AFSDANKVLE SVNEPQIDNH FGEIKAELLT FKGIPYQIKL
TSADQELREQ LPQTYVDHMT QAQTAHDNIV FMRKWLDLGN RYGNIEEVMD GVLEEVLATY
PESQLPVLVK HALEENHATN NYHFYRHVSL DEYHATYNWK TRLRMLNHFP KPTFEDIPLL
DLALSDEKVP VRRQAIVLLG MIESKEILPY LYKGLRDKSP AVRRTAGDCI SDLGYPEALP
EMVLLLDDPQ KIVRWRAAMF IFDEGNAEQL PALKAHINDN AFEVKLQIEM AISRIENGDE
ALGSVWKQMA NRTI