ID   CVNH_CERRI              Reviewed;         142 AA.
AC   P86326;
DT   01-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-SEP-2009, sequence version 1.
DT   25-MAY-2022, entry version 26.
DE   RecName: Full=Cyanovirin-N homolog {ECO:0000303|PubMed:18400178};
DE            Short=CV-N homolog {ECO:0000303|PubMed:18400178};
DE   Flags: Precursor;
OS   Ceratopteris richardii (Triangle waterfern).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Polypodiopsida; Polypodiidae; Polypodiales; Pteridineae; Pteridaceae;
OC   Parkerioideae; Ceratopteris.
OX   NCBI_TaxID=49495;
RN   [1] {ECO:0000305}
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Chatterjee A., San Miguel P., Stout S.C., Banks J., Roux S.J.;
RT   "Expressed sequence tags of cDNA clones from a C. richardii library.";
RL   Submitted (APR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000305}
RP   STRUCTURE BY NMR OF 28-142, FUNCTION, AND DISULFIDE BONDS.
RX   PubMed=18400178; DOI=10.1016/j.str.2008.01.015;
RA   Koharudin L.M.I., Viscomi A.R., Jee J.-G., Ottonello S., Gronenborn A.M.;
RT   "The evolutionarily conserved family of cyanovirin-N homologs: structures
RT   and carbohydrate specificity.";
RL   Structure 16:570-584(2008).
CC   -!- FUNCTION: Mannose-binding lectin. {ECO:0000269|PubMed:18400178}.
CC   -!- SIMILARITY: Belongs to the cyanovirin-N family. {ECO:0000305}.
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DR   EMBL; BQ087517; -; NOT_ANNOTATED_CDS; mRNA.
DR   PDB; 2JZJ; NMR; -; A=28-142.
DR   PDBsum; 2JZJ; -.
DR   AlphaFoldDB; P86326; -.
DR   SMR; P86326; -.
DR   UniLectin; P86326; -.
DR   EvolutionaryTrace; P86326; -.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.60.10; -; 1.
DR   InterPro; IPR011058; Cyanovirin-N.
DR   InterPro; IPR036673; Cyanovirin-N_sf.
DR   Pfam; PF08881; CVNH; 2.
DR   SMART; SM01111; CVNH; 1.
DR   SUPFAM; SSF51322; SSF51322; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Disulfide bond; Lectin; Signal.
FT   SIGNAL          1..27
FT                   /evidence="ECO:0000255"
FT   CHAIN           28..142
FT                   /note="Cyanovirin-N homolog"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_0000381731"
FT   DISULFID        29..128
FT                   /evidence="ECO:0000269|PubMed:18400178"
FT   DISULFID        35..49
FT                   /evidence="ECO:0000269|PubMed:18400178"
FT   DISULFID        85..100
FT                   /evidence="ECO:0000269|PubMed:18400178"
SQ   SEQUENCE   142 AA;  15223 MW;  6DBB068AEACF3284 CRC64;
     MRALAPSFRL LAGLLLLIVL SLSSANAQCN FANSCTGVEL YGYILRGDCI NEDGHPHATS
     INLNYYIGND NGRLEYPGES FGSSCVKTAL NDGHTLTASC KGADGQYHDS SMDLNYVVGN
     SYGYMEPCRA SNADHVLKSS SE