CVP7_PIMHY
ID CVP7_PIMHY Reviewed; 109 AA.
AC Q8MMH0;
DT 16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 25-MAY-2022, entry version 34.
DE RecName: Full=Cysteine-rich venom protein 7;
DE Short=cvp7;
DE Flags: Precursor;
OS Pimpla hypochondriaca (Parasitoid wasp).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Parasitoida;
OC Ichneumonoidea; Ichneumonidae; Pimplinae; Pimplini; Pimpla.
OX NCBI_TaxID=135724;
RN [1] {ECO:0000305, ECO:0000312|EMBL:CAD31108.1}
RP NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 22-26.
RC TISSUE=Venom {ECO:0000269|PubMed:15147757}, and
RC Venom gland {ECO:0000269|PubMed:15147757};
RX PubMed=15147757; DOI=10.1016/j.ibmb.2004.03.003;
RA Parkinson N.M., Conyers C., Keen J., MacNicoll A., Smith I., Audsley N.,
RA Weaver R.;
RT "Towards a comprehensive view of the primary structure of venom proteins
RT from the parasitoid wasp Pimpla hypochondriaca.";
RL Insect Biochem. Mol. Biol. 34:565-571(2004).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:15147757}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC {ECO:0000269|PubMed:15147757}.
CC -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC structurally defines this protein as a knottin. {ECO:0000305}.
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DR EMBL; AJ459957; CAD31108.1; -; mRNA.
DR AlphaFoldDB; Q8MMH0; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Knottin; Secreted; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255, ECO:0000269|PubMed:15147757"
FT CHAIN 22..109
FT /note="Cysteine-rich venom protein 7"
FT /evidence="ECO:0000255, ECO:0000269|PubMed:15147757"
FT /id="PRO_0000021050"
FT DISULFID 30..47
FT /evidence="ECO:0000305"
FT DISULFID 37..52
FT /evidence="ECO:0000305"
FT DISULFID 46..58
FT /evidence="ECO:0000305"
FT DISULFID 70..90
FT /evidence="ECO:0000255"
FT DISULFID 78..98
FT /evidence="ECO:0000255"
SQ SEQUENCE 109 AA; 12101 MW; E36701A8653B3AB3 CRC64;
MSKVFVIILV ALMVAISIAS AHRPPPNPRC LPGHSKCKYE PKKNSCCLGF QCTERNQCEL
VYPGHHGKPC GKDNLLGCIL PPPTFKPRPC GKYNLKGCKP IRPRPHPHH