ID   CW15B_XENLA             Reviewed;         230 AA.
AC   Q6DKE6;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Protein CWC15 homolog B;
GN   Name=cwc15-b;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in pre-mRNA splicing as component of the
CC       spliceosome. {ECO:0000250|UniProtKB:Q9P013}.
CC   -!- SUBUNIT: Identified in the spliceosome C complex.
CC       {ECO:0000250|UniProtKB:Q9P013}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9P013}.
CC   -!- SIMILARITY: Belongs to the CWC15 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC074156; AAH74156.1; -; mRNA.
DR   RefSeq; NP_001086072.1; NM_001092603.1.
DR   AlphaFoldDB; Q6DKE6; -.
DR   MaxQB; Q6DKE6; -.
DR   PRIDE; Q6DKE6; -.
DR   GeneID; 444501; -.
DR   KEGG; xla:444501; -.
DR   CTD; 444501; -.
DR   Xenbase; XB-GENE-6254901; cwc15.L.
DR   OMA; KGYEDRD; -.
DR   OrthoDB; 1576404at2759; -.
DR   Proteomes; UP000186698; Chromosome 2L.
DR   Bgee; 444501; Expressed in testis and 19 other tissues.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR006973; Cwf_Cwc_15.
DR   PANTHER; PTHR12718; PTHR12718; 1.
DR   Pfam; PF04889; Cwf_Cwc_15; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..230
FT                   /note="Protein CWC15 homolog B"
FT                   /id="PRO_0000291549"
FT   REGION          1..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          121..165
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        35..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..125
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   230 AA;  26654 MW;  7F236A85219F5729 CRC64;
     MTTAARPTFE PARGGRGKGE SDLSQLSKQY SSRDLPSHTK IKYRQTTQDA PEEVRSRDFR
     RELEERERVA VRDKNRDRPT REHTSSVSKK PRLDQIPAAN LDADDPLTDE DADEDSDEDS
     DDDTAALLAE LEKIKKERAE EQVRKELEQK AEEERIRMEN ILSGNPLLNL TGPAAQSQAS
     FKVKRRWDDD VVFKNCAKGV DEMKKRQDKR FVNDTLRSEF HKKFMEKYVK