CWC15_ASHGO
ID CWC15_ASHGO Reviewed; 184 AA.
AC Q750V7;
DT 30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 81.
DE RecName: Full=Pre-mRNA-splicing factor CWC15;
GN Name=CWC15; OrderedLocusNames=AGL168W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CWC15 family. {ECO:0000305}.
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DR EMBL; AE016820; AAS54323.1; -; Genomic_DNA.
DR RefSeq; NP_986499.1; NM_211561.1.
DR AlphaFoldDB; Q750V7; -.
DR STRING; 33169.AAS54323; -.
DR EnsemblFungi; AAS54323; AAS54323; AGOS_AGL168W.
DR GeneID; 4622792; -.
DR KEGG; ago:AGOS_AGL168W; -.
DR eggNOG; KOG3228; Eukaryota.
DR HOGENOM; CLU_100667_0_0_1; -.
DR InParanoid; Q750V7; -.
DR OMA; NIKEHAT; -.
DR Proteomes; UP000000591; Chromosome VII.
DR GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0005684; C:U2-type spliceosomal complex; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IBA:GO_Central.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR InterPro; IPR006973; Cwf_Cwc_15.
DR PANTHER; PTHR12718; PTHR12718; 2.
PE 3: Inferred from homology;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT CHAIN 1..184
FT /note="Pre-mRNA-splicing factor CWC15"
FT /id="PRO_0000218236"
FT REGION 1..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..73
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 90..108
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 151..184
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 184 AA; 19801 MW; 8A6B0622E0F4ACB6 CRC64;
MTTSHRPQLE ARSGTKSGVA GEYVPTGVKH ARLLPGHRTV KRRREGGATA EDEERERAGA
ETRTVDCNEG TDELAGEGRS AGSGDGDEAS SAEDSSDADD EDDVDNPEEL RRELEALRAS
KTGAKTGAKT GAKTGEKGAG GGGWRAGAVF GRQKRRREQA EGRAYRNDVT QSEYHQDFLR
RLTK
