CWC15_CANGA
ID CWC15_CANGA Reviewed; 143 AA.
AC Q6FVL2;
DT 13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Pre-mRNA-splicing factor CWC15;
GN Name=CWC15; OrderedLocusNames=CAGL0E01023g;
OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS Y-65) (Yeast) (Torulopsis glabrata).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC Nakaseomyces/Candida clade.
OX NCBI_TaxID=284593;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CWC15 family. {ECO:0000305}.
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DR EMBL; CR380951; CAG58651.1; -; Genomic_DNA.
DR RefSeq; XP_445732.1; XM_445732.1.
DR AlphaFoldDB; Q6FVL2; -.
DR STRING; 5478.XP_445732.1; -.
DR EnsemblFungi; CAG58651; CAG58651; CAGL0E01023g.
DR GeneID; 2887413; -.
DR KEGG; cgr:CAGL0E01023g; -.
DR CGD; CAL0129014; CAGL0E01023g.
DR VEuPathDB; FungiDB:CAGL0E01023g; -.
DR eggNOG; KOG3228; Eukaryota.
DR HOGENOM; CLU_1805920_0_0_1; -.
DR InParanoid; Q6FVL2; -.
DR Proteomes; UP000002428; Chromosome E.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0005684; C:U2-type spliceosomal complex; IEA:EnsemblFungi.
DR GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR InterPro; IPR006973; Cwf_Cwc_15.
DR Pfam; PF04889; Cwf_Cwc_15; 1.
PE 3: Inferred from homology;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT CHAIN 1..143
FT /note="Pre-mRNA-splicing factor CWC15"
FT /id="PRO_0000218238"
FT REGION 1..83
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 43..81
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 143 AA; 15695 MW; 933DA7FCAD95C974 CRC64;
MTTAHRPQLE ARNGAKGALV PTGTEHARLL PGHTELKARK PKNKTTSQIQ TSSDAGSVDD
STSAGTNIGT GSATLGPSQV QKMIQPLEVE DKKDIKLVKK EDDSVSWGKT AFSRRKKVVK
PEKFTNDTVR SQKHKEFLNR FVK