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CWC15_DEBHA
ID   CWC15_DEBHA             Reviewed;         226 AA.
AC   Q6BP48; B5RU25;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 2.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Pre-mRNA-splicing factor CWC15;
GN   Name=CWC15; OrderedLocusNames=DEHA2E16566g;
OS   Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS   / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX   NCBI_TaxID=284592;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CWC15 family. {ECO:0000305}.
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DR   EMBL; CR382137; CAR65837.1; -; Genomic_DNA.
DR   RefSeq; XP_002770494.1; XM_002770448.1.
DR   AlphaFoldDB; Q6BP48; -.
DR   SMR; Q6BP48; -.
DR   STRING; 4959.XP_002770494.1; -.
DR   EnsemblFungi; CAR65837; CAR65837; DEHA2E16566g.
DR   GeneID; 8998770; -.
DR   KEGG; dha:DEHA2E16566g; -.
DR   VEuPathDB; FungiDB:DEHA2E16566g; -.
DR   eggNOG; KOG3228; Eukaryota.
DR   HOGENOM; CLU_068312_1_0_1; -.
DR   InParanoid; Q6BP48; -.
DR   OMA; NCARSEP; -.
DR   OrthoDB; 1576404at2759; -.
DR   Proteomes; UP000000599; Chromosome E.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR006973; Cwf_Cwc_15.
DR   PANTHER; PTHR12718; PTHR12718; 1.
DR   Pfam; PF04889; Cwf_Cwc_15; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..226
FT                   /note="Pre-mRNA-splicing factor CWC15"
FT                   /id="PRO_0000218239"
FT   REGION          1..31
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          78..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          126..167
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        14..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        78..120
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   226 AA;  26172 MW;  554762D8FDD7A1C7 CRC64;
     MTTNHRPTLE SKRGKAESIS NTIFHSRSLP QHTSLKYRGD IRKPKVDTKI GKQAVEELKK
     DLLLNEGKLE DSLKINKSLT DGDHSMDEHI SKTIDNQEDE RDYNRQEYDE RSIGKEEYSG
     SEDDSGDDSE DETAQLMEEL AKIKKERQEE QEKLELQNKL DKTKVSNPLV QVVGASTEAN
     FKIKKSWRDS TAFKKQNSQN KNDDETFTND TLNSEFHQNF LTKYIR
 
 
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