ID   CWC15_XENTR             Reviewed;         227 AA.
AC   Q0VFP5;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   03-AUG-2022, entry version 74.
DE   RecName: Full=Protein CWC15 homolog;
GN   Name=cwc15;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in pre-mRNA splicing as component of the
CC       spliceosome. {ECO:0000250|UniProtKB:Q9P013}.
CC   -!- SUBUNIT: Identified in the spliceosome C complex.
CC       {ECO:0000250|UniProtKB:Q9P013}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q9P013}.
CC   -!- SIMILARITY: Belongs to the CWC15 family. {ECO:0000305}.
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DR   EMBL; BC118751; AAI18752.1; -; mRNA.
DR   RefSeq; NP_001072201.1; NM_001078733.1.
DR   RefSeq; XP_012812670.1; XM_012957216.2.
DR   AlphaFoldDB; Q0VFP5; -.
DR   STRING; 8364.ENSXETP00000063493; -.
DR   GeneID; 779647; -.
DR   KEGG; xtr:779647; -.
DR   CTD; 51503; -.
DR   Xenbase; XB-GENE-987018; cwc15.
DR   eggNOG; KOG3228; Eukaryota.
DR   HOGENOM; CLU_068312_0_1_1; -.
DR   InParanoid; Q0VFP5; -.
DR   OrthoDB; 1576404at2759; -.
DR   PhylomeDB; Q0VFP5; -.
DR   Reactome; R-XTR-72163; mRNA Splicing - Major Pathway.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000007076; Expressed in 2-cell stage embryo and 13 other tissues.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR006973; Cwf_Cwc_15.
DR   PANTHER; PTHR12718; PTHR12718; 1.
DR   Pfam; PF04889; Cwf_Cwc_15; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..227
FT                   /note="Protein CWC15 homolog"
FT                   /id="PRO_0000291550"
FT   REGION          1..130
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          121..165
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        35..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        104..125
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   227 AA;  26163 MW;  9DAE54576D9F8C72 CRC64;
     MTTAARPTFE PARGGRGKGE ADLSQLSKQY SSRDLPSHTK IKYRQATQDA PEEVRSRDFR
     RELEERERVA VREKNRDRPT REHASSVSKK PRLDQIPAAN LDADDPLTDE DADDDSDEDS
     DDDTAALLAE LEKIKKERAE EQARKELEQK AEEERIRMEN ILSGNPLLNL TGPAQSVAAF
     KVKRRWDDDV VFKNCAKGVD EMKKDKRFVN DTLRSEFHKK FMEKYIK