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CWC15_YARLI
ID   CWC15_YARLI             Reviewed;         215 AA.
AC   Q6C0E6;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 71.
DE   RecName: Full=Pre-mRNA-splicing factor CWC15;
GN   Name=CWC15; OrderedLocusNames=YALI0F25421g;
OS   Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Dipodascaceae; Yarrowia.
OX   NCBI_TaxID=284591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CLIB 122 / E 150;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CWC15 family. {ECO:0000305}.
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DR   EMBL; CR382132; CAG78677.1; -; Genomic_DNA.
DR   RefSeq; XP_505866.1; XM_505866.1.
DR   AlphaFoldDB; Q6C0E6; -.
DR   STRING; 4952.CAG78677; -.
DR   EnsemblFungi; CAG78677; CAG78677; YALI0_F25421g.
DR   GeneID; 2908528; -.
DR   KEGG; yli:YALI0F25421g; -.
DR   VEuPathDB; FungiDB:YALI0_F25421g; -.
DR   HOGENOM; CLU_068312_0_1_1; -.
DR   InParanoid; Q6C0E6; -.
DR   OMA; KGYEDRD; -.
DR   Proteomes; UP000001300; Chromosome F.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0000974; C:Prp19 complex; IEA:EnsemblFungi.
DR   GO; GO:0003723; F:RNA binding; ISS:UniProtKB.
DR   GO; GO:0045292; P:mRNA cis splicing, via spliceosome; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR006973; Cwf_Cwc_15.
DR   PANTHER; PTHR12718; PTHR12718; 1.
DR   Pfam; PF04889; Cwf_Cwc_15; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..215
FT                   /note="Pre-mRNA-splicing factor CWC15"
FT                   /id="PRO_0000218243"
FT   REGION          1..34
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          72..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          60..162
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..31
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..100
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        101..125
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   215 AA;  24732 MW;  5A4D2137B8B6A59D CRC64;
     MTTAHRPTFD PARGKSNTQA AGSISHTRSL PSHTKLKYRY ARISTNTDAM RKTLLENEGG
     LKQAATKLVA EQQQAETQVQ DSEKELSDEV KAKIIEENRD DDDSGSDDEE SDSDDSDSDS
     DDEDELLRIE LERIKQERAQ AKAREEERLA LEEAKAREEQ VAFGNPLMNP VAIKRKWNED
     VVFRNQTKQA RKEDSYVNDL IRSDFHRKFM NRYVR
 
 
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