ID   34KD_MYCBO              Reviewed;         303 AA.
AC   P65638; A0A1R3XWX9; P71556; X2BGJ1;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=34 kDa antigenic protein homolog;
GN   OrderedLocusNames=BQ2027_MB0979;
OS   Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium tuberculosis complex.
OX   NCBI_TaxID=233413;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=12788972; DOI=10.1073/pnas.1130426100;
RA   Garnier T., Eiglmeier K., Camus J.-C., Medina N., Mansoor H., Pryor M.,
RA   Duthoy S., Grondin S., Lacroix C., Monsempe C., Simon S., Harris B.,
RA   Atkin R., Doggett J., Mayes R., Keating L., Wheeler P.R., Parkhill J.,
RA   Barrell B.G., Cole S.T., Gordon S.V., Hewinson R.G.;
RT   "The complete genome sequence of Mycobacterium bovis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:7877-7882(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC   STRAIN=ATCC BAA-935 / AF2122/97;
RX   PubMed=28385856; DOI=10.1128/genomea.00157-17;
RA   Malone K.M., Farrell D., Stuber T.P., Schubert O.T., Aebersold R.,
RA   Robbe-Austerman S., Gordon S.V.;
RT   "Updated reference genome sequence and annotation of Mycobacterium bovis
RT   AF2122/97.";
RL   Genome Announc. 5:E00157-E00157(2017).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: To M.paratuberculosis 34 kDa antigenic protein.
CC       {ECO:0000305}.
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DR   EMBL; LT708304; SIT99577.1; -; Genomic_DNA.
DR   RefSeq; NP_854636.1; NC_002945.3.
DR   RefSeq; WP_003404875.1; NC_002945.4.
DR   AlphaFoldDB; P65638; -.
DR   EnsemblBacteria; SIT99577; SIT99577; BQ2027_MB0979.
DR   PATRIC; fig|233413.5.peg.1066; -.
DR   OMA; PRPKYDP; -.
DR   Proteomes; UP000001419; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR035166; DUF5336.
DR   Pfam; PF17270; DUF5336; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..303
FT                   /note="34 kDa antigenic protein homolog"
FT                   /id="PRO_0000064362"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          194..303
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        213..259
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        271..297
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   303 AA;  30204 MW;  4FE18A077FDFD8B5 CRC64;
     MTYSPGNPGY PQAQPAGSYG GVTPSFAHAD EGASKLPMYL NIAVAVLGLA AYFASFGPMF
     TLSTELGGGD GAVSGDTGLP VGVALLAALL AGVALVPKAK SHVTVVAVLG VLGVFLMVSA
     TFNKPSAYST GWALWVVLAF IVFQAVAAVL ALLVETGAIT APAPRPKFDP YGQYGRYGQY
     GQYGVQPGGY YGQQGAQQAA GLQSPGPQQS PQPPGYGSQY GGYSSSPSQS GSGYTAQPPA
     QPPAQSGSQQ SHQGPSTPPT GFPSFSPPPP VSAGTGSQAG SAPVNYSNPS GGEQSSSPGG
     APV