ID   CWC25_ASHGO             Reviewed;         138 AA.
AC   Q75AR4;
DT   30-AUG-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 59.
DE   RecName: Full=Pre-mRNA-splicing factor CWC25;
GN   Name=CWC25; OrderedLocusNames=ADL144C;
OS   Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS   (Yeast) (Eremothecium gossypii).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX   NCBI_TaxID=284811;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=15001715; DOI=10.1126/science.1095781;
RA   Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA   Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA   Gaffney T.D., Philippsen P.;
RT   "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT   cerevisiae genome.";
RL   Science 304:304-307(2004).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX   PubMed=23749448; DOI=10.1534/g3.112.002881;
RA   Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT   "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT   loci, numerous translocations, lack of transposons, and distinct gene
RT   duplications.";
RL   G3 (Bethesda) 3:1225-1239(2013).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CWC25 family. {ECO:0000305}.
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DR   EMBL; AE016817; AAS51776.1; -; Genomic_DNA.
DR   RefSeq; NP_983952.1; NM_209305.1.
DR   AlphaFoldDB; Q75AR4; -.
DR   SMR; Q75AR4; -.
DR   EnsemblFungi; AAS51776; AAS51776; AGOS_ADL144C.
DR   GeneID; 4620094; -.
DR   KEGG; ago:AGOS_ADL144C; -.
DR   HOGENOM; CLU_1854782_0_0_1; -.
DR   InParanoid; Q75AR4; -.
DR   Proteomes; UP000000591; Chromosome IV.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR019339; CIR_N_dom.
DR   Pfam; PF10197; Cir_N; 1.
PE   3: Inferred from homology;
KW   mRNA processing; mRNA splicing; Nucleus; Reference proteome; Spliceosome.
FT   CHAIN           1..138
FT                   /note="Pre-mRNA-splicing factor CWC25"
FT                   /id="PRO_0000079583"
FT   REGION          28..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        77..91
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   138 AA;  14831 MW;  340E1F8DA654253C CRC64;
     MDLNLLKSWN PQLQKNRKKV YEAQQELLKS ARKPADDGTS GGGLDWMYEG QPAPQRKVRK
     RRTRTRKPKQ VPKDAQGKLQ ESLQTARSDA PEGTCSPDET AAARGGQQGA PVEVSAKSPA
     KAVAEARGGP GSSGVHGE