ID   CWC25_CANGA             Reviewed;         176 AA.
AC   Q6FP02;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Pre-mRNA-splicing factor CWC25;
GN   Name=CWC25; OrderedLocusNames=CAGL0J07700g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CWC25 family. {ECO:0000305}.
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DR   EMBL; CR380956; CAG60993.1; -; Genomic_DNA.
DR   RefSeq; XP_448042.1; XM_448042.1.
DR   AlphaFoldDB; Q6FP02; -.
DR   SMR; Q6FP02; -.
DR   STRING; 5478.XP_448042.1; -.
DR   EnsemblFungi; CAG60993; CAG60993; CAGL0J07700g.
DR   GeneID; 2889902; -.
DR   KEGG; cgr:CAGL0J07700g; -.
DR   CGD; CAL0133598; CAGL0J07700g.
DR   VEuPathDB; FungiDB:CAGL0J07700g; -.
DR   eggNOG; KOG3869; Eukaryota.
DR   HOGENOM; CLU_025093_3_1_1; -.
DR   InParanoid; Q6FP02; -.
DR   Proteomes; UP000002428; Chromosome J.
DR   GO; GO:0005684; C:U2-type spliceosomal complex; IEA:EnsemblFungi.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IEA:EnsemblFungi.
DR   InterPro; IPR019339; CIR_N_dom.
DR   Pfam; PF10197; Cir_N; 1.
DR   SMART; SM01083; Cir_N; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..176
FT                   /note="Pre-mRNA-splicing factor CWC25"
FT                   /id="PRO_0000079586"
FT   REGION          139..176
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          25..58
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   176 AA;  20659 MW;  A5A68FBD50BA631A CRC64;
     MGTGDLNLLK SWNPKLVKNR KKVWEKEQRL LEEDEKIRKR QLEIAKEKEE EELLAGRDST
     KGRKTGLEWM YQDDPTAKED YLLGKKKLDT TVIKKAEVME ENQTPLTKIN KTTVIPDAIY
     SKEDPMARFG TKVKRNKVVK KEPVKPLRGK TTNEPRTDNI KPKSDYKKRL QEELDY