ID   CWC26_ASPFU             Reviewed;         344 AA.
AC   Q4W9Z9;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Pre-mRNA-splicing factor cwc26;
GN   Name=cwc26; ORFNames=AFUA_4G03160;
OS   Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC
OS   A1100) (Aspergillus fumigatus).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC   Aspergillus subgen. Fumigati.
OX   NCBI_TaxID=330879;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100;
RX   PubMed=16372009; DOI=10.1038/nature04332;
RA   Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., Arroyo J.,
RA   Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., Bowyer P.,
RA   Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., Farman M.L.,
RA   Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., Fosker N.,
RA   Fraser A., Garcia J.L., Garcia M.J., Goble A., Goldman G.H., Gomi K.,
RA   Griffith-Jones S., Gwilliam R., Haas B.J., Haas H., Harris D.E.,
RA   Horiuchi H., Huang J., Humphray S., Jimenez J., Keller N., Khouri H.,
RA   Kitamoto K., Kobayashi T., Konzack S., Kulkarni R., Kumagai T., Lafton A.,
RA   Latge J.-P., Li W., Lord A., Lu C., Majoros W.H., May G.S., Miller B.L.,
RA   Mohamoud Y., Molina M., Monod M., Mouyna I., Mulligan S., Murphy L.D.,
RA   O'Neil S., Paulsen I., Penalva M.A., Pertea M., Price C., Pritchard B.L.,
RA   Quail M.A., Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U.,
RA   Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M.,
RA   Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., Sanchez-Ferrero J.C.,
RA   Saunders D., Seeger K., Squares R., Squares S., Takeuchi M., Tekaia F.,
RA   Turner G., Vazquez de Aldana C.R., Weidman J., White O., Woodward J.R.,
RA   Yu J.-H., Fraser C.M., Galagan J.E., Asai K., Machida M., Hall N.,
RA   Barrell B.G., Denning D.W.;
RT   "Genomic sequence of the pathogenic and allergenic filamentous fungus
RT   Aspergillus fumigatus.";
RL   Nature 438:1151-1156(2005).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CWC26 family. {ECO:0000305}.
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DR   EMBL; AAHF01000016; EAL84464.1; -; Genomic_DNA.
DR   RefSeq; XP_746502.1; XM_741409.1.
DR   AlphaFoldDB; Q4W9Z9; -.
DR   SMR; Q4W9Z9; -.
DR   STRING; 746128.CADAFUBP00009716; -.
DR   PRIDE; Q4W9Z9; -.
DR   EnsemblFungi; EAL84464; EAL84464; AFUA_4G03160.
DR   GeneID; 3504064; -.
DR   KEGG; afm:AFUA_4G03160; -.
DR   VEuPathDB; FungiDB:Afu4g03160; -.
DR   eggNOG; KOG2654; Eukaryota.
DR   HOGENOM; CLU_024195_0_0_1; -.
DR   InParanoid; Q4W9Z9; -.
DR   OMA; EKYMSGP; -.
DR   OrthoDB; 1558074at2759; -.
DR   Proteomes; UP000002530; Chromosome 4.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0070274; C:RES complex; IBA:GO_Central.
DR   GO; GO:0005684; C:U2-type spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; IBA:GO_Central.
DR   InterPro; IPR018609; Bud13.
DR   Pfam; PF09736; Bud13; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; mRNA processing; mRNA splicing; Nucleus;
KW   Reference proteome; Spliceosome.
FT   CHAIN           1..344
FT                   /note="Pre-mRNA-splicing factor cwc26"
FT                   /id="PRO_0000079598"
FT   REGION          14..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          211..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          156..246
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        166..188
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   344 AA;  37806 MW;  56EED67980CE3598 CRC64;
     MPPSSLAEYL AKKYLTADPA TDRPKKKRKK TKTVDTAGDG LIIADDDPPD LRTSATNFDN
     EDDEGPSLVT SVRSAEFRRA KKSNWRTVGG PATGSSNAND ERDAADAILA SAAAESAARR
     GEGEGGDDEA PAVVDEADAD DGGELRMESG ARAGLQTAEQ TAAMVAAQER RKKAEAARHR
     ERPAEAQETI YRDASGRIIN VALKRAEARR AEQEKREKEE AAKEALMGDV QRAEREARRQ
     QIQEARAMPL ARTIEDDALN EELKAQQRWN DPAAGFLTKT KGPGVSVTGK PLYKGAFQPN
     RYGIRPGHRW DGVDRGNGFE KEWFAARNKK GRLEALDYQW QMDE