ID   CWH36_YEAST             Reviewed;         130 AA.
AC   P25603;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1992, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Putative uncharacterized protein CWH36;
GN   Name=CWH36; OrderedLocusNames=YCL007C; ORFNames=YCL7C;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=1574125; DOI=10.1038/357038a0;
RA   Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA   Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA   Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA   Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA   Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA   Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA   Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA   Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA   Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA   Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA   Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA   Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA   Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA   Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA   Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA   Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA   Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA   Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA   Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA   Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA   Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA   Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA   Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA   Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA   Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA   Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA   Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA   Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA   Sgouros J.G.;
RT   "The complete DNA sequence of yeast chromosome III.";
RL   Nature 357:38-46(1992).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   FUNCTION.
RX   PubMed=7992502; DOI=10.1002/yea.320100804;
RA   Ram A.F., Wolters A., Ten Hoopen R., Klis F.M.;
RT   "A new approach for isolating cell wall mutants in Saccharomyces cerevisiae
RT   by screening for hypersensitivity to calcofluor white.";
RL   Yeast 10:1019-1030(1994).
RN   [4]
RP   REVISION OF FUNCTION.
RX   PubMed=14594803; DOI=10.1074/jbc.m310680200;
RA   Davis-Kaplan S.R., McVey Ward D., Shiflett S.L., Kaplan J.;
RT   "Genome-wide analysis of iron-dependent growth reveals a novel yeast gene
RT   required for vacuolar acidification.";
RL   J. Biol. Chem. 279:4322-4329(2004).
CC   -!- MISCELLANEOUS: Almost completely overlaps VMA9. {ECO:0000305}.
CC   -!- CAUTION: Product of a dubious gene prediction unlikely to encode a
CC       functional protein. Was originally (PubMed:7992502) thought to function
CC       in calcofluor white resistance, hence the name CWH36, but this
CC       phenotype was later (PubMed:14594803) attributed to the overlapping
CC       gene VMA9. Because of that it is not part of the S.cerevisiae S288c
CC       complete/reference proteome set. {ECO:0000305|PubMed:14594803,
CC       ECO:0000305|PubMed:24374639, ECO:0000305|PubMed:7992502}.
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DR   EMBL; X59720; CAA42352.1; -; Genomic_DNA.
DR   PIR; S19409; S19409.
DR   AlphaFoldDB; P25603; -.
DR   SMR; P25603; -.
DR   DIP; DIP-5350N; -.
DR   IntAct; P25603; 1.
DR   STRING; 4932.YCL007C; -.
DR   PaxDb; P25603; -.
DR   EnsemblFungi; YCL007C_mRNA; YCL007C; YCL007C.
DR   SGD; S000000513; YCL007C.
DR   HOGENOM; CLU_1939740_0_0_1; -.
PE   5: Uncertain;
FT   CHAIN           1..130
FT                   /note="Putative uncharacterized protein CWH36"
FT                   /id="PRO_0000079617"
FT   REGION          1..28
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   130 AA;  15469 MW;  9820E892291BD709 CRC64;
     MELAKERNGP HQKHHGQCQN HCTSPNTVRQ NKTNKLLLVK KKGKLVIWRH IVKKMLHIRL
     VVLWSHYPEQ HGHGTNHYEY TNNSIAKLDA QRVSRRRRKK REAERRDYDT YKLLITLCSL
     LFVGPLFLKV