ID   34KD_MYCPA              Reviewed;         298 AA.
AC   Q04959;
DT   01-JUN-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-1994, sequence version 1.
DT   25-MAY-2022, entry version 98.
DE   RecName: Full=34 kDa antigenic protein;
GN   OrderedLocusNames=MAP_0900;
OS   Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)
OS   (Mycobacterium paratuberculosis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium; Mycobacterium avium complex (MAC).
OX   NCBI_TaxID=262316;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8335649; DOI=10.1128/jb.175.15.4930-4935.1993;
RA   Gilot P., de Kesel M., Machtelinckx L., Coene M., Cocito C.;
RT   "Isolation and sequencing of the gene coding for an antigenic 34-kilodalton
RT   protein of Mycobacterium paratuberculosis.";
RL   J. Bacteriol. 175:4930-4935(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-968 / K-10;
RX   PubMed=16116077; DOI=10.1073/pnas.0505662102;
RA   Li L., Bannantine J.P., Zhang Q., Amonsin A., May B.J., Alt D., Banerji N.,
RA   Kanjilal S., Kapur V.;
RT   "The complete genome sequence of Mycobacterium avium subspecies
RT   paratuberculosis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:12344-12349(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: To M.tuberculosis RV0954. {ECO:0000305}.
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DR   EMBL; X68102; CAA48221.1; -; Genomic_DNA.
DR   EMBL; AE016958; AAS03217.1; -; Genomic_DNA.
DR   PIR; A40616; A40616.
DR   RefSeq; WP_003877490.1; NC_002944.2.
DR   AlphaFoldDB; Q04959; -.
DR   STRING; 262316.MAP_0900; -.
DR   EnsemblBacteria; AAS03217; AAS03217; MAP_0900.
DR   KEGG; mpa:MAP_0900; -.
DR   eggNOG; ENOG5033AAF; Bacteria.
DR   HOGENOM; CLU_086639_0_0_11; -.
DR   OMA; PRPKYDP; -.
DR   Proteomes; UP000000580; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR035166; DUF5336.
DR   Pfam; PF17270; DUF5336; 1.
PE   4: Predicted;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..298
FT                   /note="34 kDa antigenic protein"
FT                   /id="PRO_0000064363"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        134..154
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          188..298
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        197..213
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        228..250
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        261..291
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   298 AA;  29565 MW;  B2E57AA2077F0D3D CRC64;
     MTYSPGSPGY PPAQSGGTYA GATPSFAKDD DGKSKLPLYL NIAVVALGFA AYLLNFGPTF
     TIGADLGPGI GGRAGDAGTA VVVALLAALL AGLGLLPKAK SYVGVVAVVA VLAALLAITE
     TINLPAGFAI GWAMWPLVAC VVLQAIAAVV VVLLDAGVIT APAPRPKYDP YAQYGQYGQY
     GQYGQQPYYG QPGGQPGGQP GGQQHSPQGY GSQYGGYGQG GAPTGGFGAQ PSPQSGPQQS
     AQQQGPSTPP TGFPSFSPPP NVGGGSDSGS ATANYSEQAG GQQSYGQEPS SPSGPTPA