CX038_MOUSE
ID CX038_MOUSE Reviewed; 320 AA.
AC Q8C5K5; Q3TFM9; Q8CF12;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Uncharacterized protein CXorf38 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=C57BL/6J; TISSUE=Medulla oblongata, Pancreas, and Placenta;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP METHYLATION [LARGE SCALE ANALYSIS] AT ARG-61, AND IDENTIFICATION BY MASS
RP SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, and Embryo;
RX PubMed=24129315; DOI=10.1074/mcp.o113.027870;
RA Guo A., Gu H., Zhou J., Mulhern D., Wang Y., Lee K.A., Yang V., Aguiar M.,
RA Kornhauser J., Jia X., Ren J., Beausoleil S.A., Silva J.C., Vemulapalli V.,
RA Bedford M.T., Comb M.J.;
RT "Immunoaffinity enrichment and mass spectrometry analysis of protein
RT methylation.";
RL Mol. Cell. Proteomics 13:372-387(2014).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8C5K5-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8C5K5-2; Sequence=VSP_014623;
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DR EMBL; AK007661; BAC25180.1; -; mRNA.
DR EMBL; AK078166; BAC37156.1; -; mRNA.
DR EMBL; AK146041; BAE26853.1; -; mRNA.
DR EMBL; AK169085; BAE40869.1; -; mRNA.
DR CCDS; CCDS30024.1; -. [Q8C5K5-1]
DR RefSeq; NP_780350.1; NM_175141.6. [Q8C5K5-1]
DR RefSeq; XP_006527761.1; XM_006527698.3. [Q8C5K5-1]
DR AlphaFoldDB; Q8C5K5; -.
DR STRING; 10090.ENSMUSP00000059095; -.
DR CarbonylDB; Q8C5K5; -.
DR iPTMnet; Q8C5K5; -.
DR PhosphoSitePlus; Q8C5K5; -.
DR EPD; Q8C5K5; -.
DR MaxQB; Q8C5K5; -.
DR PaxDb; Q8C5K5; -.
DR PeptideAtlas; Q8C5K5; -.
DR PRIDE; Q8C5K5; -.
DR Antibodypedia; 55857; 7 antibodies from 6 providers.
DR DNASU; 69155; -.
DR Ensembl; ENSMUST00000060108; ENSMUSP00000059095; ENSMUSG00000044148. [Q8C5K5-1]
DR GeneID; 69155; -.
DR KEGG; mmu:69155; -.
DR UCSC; uc009sqy.1; mouse. [Q8C5K5-1]
DR MGI; MGI:1916405; 1810030O07Rik.
DR VEuPathDB; HostDB:ENSMUSG00000044148; -.
DR eggNOG; ENOG502QR6P; Eukaryota.
DR GeneTree; ENSGT00390000006290; -.
DR HOGENOM; CLU_064748_0_0_1; -.
DR InParanoid; Q8C5K5; -.
DR OMA; DGCEYET; -.
DR TreeFam; TF333077; -.
DR BioGRID-ORCS; 69155; 0 hits in 71 CRISPR screens.
DR PRO; PR:Q8C5K5; -.
DR Proteomes; UP000000589; Chromosome X.
DR RNAct; Q8C5K5; protein.
DR Bgee; ENSMUSG00000044148; Expressed in cardiac muscle of left ventricle and 254 other tissues.
DR ExpressionAtlas; Q8C5K5; baseline and differential.
DR Genevisible; Q8C5K5; MM.
DR InterPro; IPR027897; DUF4559.
DR PANTHER; PTHR35083; PTHR35083; 1.
DR Pfam; PF15112; DUF4559; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Methylation; Phosphoprotein; Reference proteome.
FT CHAIN 1..320
FT /note="Uncharacterized protein CXorf38 homolog"
FT /id="PRO_0000079733"
FT REGION 299..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 61
FT /note="Omega-N-methylarginine"
FT /evidence="ECO:0007744|PubMed:24129315"
FT MOD_RES 315
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q8TB03"
FT VAR_SEQ 1..119
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_014623"
FT CONFLICT 163
FT /note="N -> K (in Ref. 1; BAC25180)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 320 AA; 36589 MW; BF32B585BED7CCE2 CRC64;
MVVSELAARL NCAEYKNWVK AGHCLLLLRS CLQGFIDREV LSFHRGLLAA VPGLGPHATC
RGGSRCSPRA RQFQPQCQVC AEWKHEILRH HINRNGDVHW GNCKPGLWPK DPWEVAKAFM
PRGLADKRGP EECDAVALLS LINSCDHFVV DRKKVTEVIK CRNEIMHSSE MKVSSTWLRD
FQIKIQNFLN EFKNIPEIVA VYSRIEQLLT SDWAVHIPEE DERDGCEFEI GSYLSVSQIH
EIEIELLKEK LQEMYLQAAE EEMLPEEISN QLDVVKGFLG SNTDLRNGLT EDLQKLESLH
LQHQKQTSKD AGRQTPERKA
