CX049_MOUSE
ID CX049_MOUSE Reviewed; 513 AA.
AC Q9D454;
DT 22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Uncharacterized protein CXorf49 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-84 AND SER-123, AND
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
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DR EMBL; AK016789; BAB30431.1; -; mRNA.
DR CCDS; CCDS49612.1; -.
DR RefSeq; NP_081944.1; NM_027668.1.
DR AlphaFoldDB; Q9D454; -.
DR SMR; Q9D454; -.
DR iPTMnet; Q9D454; -.
DR PhosphoSitePlus; Q9D454; -.
DR PaxDb; Q9D454; -.
DR PRIDE; Q9D454; -.
DR Ensembl; ENSMUST00000096421; ENSMUSP00000094154; ENSMUSG00000071749.
DR GeneID; 71088; -.
DR KEGG; mmu:71088; -.
DR UCSC; uc011ztd.1; mouse.
DR MGI; MGI:1918338; 4933412E24Rik.
DR VEuPathDB; HostDB:ENSMUSG00000071749; -.
DR eggNOG; KOG3544; Eukaryota.
DR GeneTree; ENSGT00390000015252; -.
DR HOGENOM; CLU_037026_1_0_1; -.
DR InParanoid; Q9D454; -.
DR OMA; CILLQME; -.
DR OrthoDB; 756568at2759; -.
DR PhylomeDB; Q9D454; -.
DR TreeFam; TF339260; -.
DR BioGRID-ORCS; 71088; 4 hits in 73 CRISPR screens.
DR PRO; PR:Q9D454; -.
DR Proteomes; UP000000589; Chromosome 15.
DR RNAct; Q9D454; protein.
DR Bgee; ENSMUSG00000071749; Expressed in seminiferous tubule of testis and 4 other tissues.
DR Genevisible; Q9D454; MM.
DR InterPro; IPR027822; DUF4641.
DR PANTHER; PTHR31866; PTHR31866; 1.
DR Pfam; PF15483; DUF4641; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..513
FT /note="Uncharacterized protein CXorf49 homolog"
FT /id="PRO_0000343896"
FT REGION 1..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 210..229
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 236..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 390..414
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 453..481
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 236..259
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 43
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q3KR64"
FT MOD_RES 84
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
FT MOD_RES 123
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:21183079"
SQ SEQUENCE 513 AA; 55249 MW; 3127BC4AF8837188 CRC64;
MGSSEEQSVP GDDFYEESGD LNTGLSLVLR PAKSNEGESS LSSPKGSKLT LVSQLEASEN
PSVVLWAGEY CPDSLVPEEE RVGSPMDEKV VGLDFLSQPS VETTATGQQV TNLETKGARE
HPSPESVCAE TEAGSIRRAP QASEEAKFAA SAGTFFPKGL EQSRSWVTPR KSTTSRMVIG
ENVHHPTSEP EPLDELNEVQ MMRVTICLKD GNHGNQAKNS GPAETGDLAR HSNVQTRDSF
MRMPSSLLVS TTRGLTSGVE RQASKEPEPF SSKKKQGTLW GKGGSKSSYP EAAAGIGALP
KASPRKKMAQ KKKPLWDASA VTLGRAFHQW GQRLKSAPAE PATFPPISGV GLPGRSNKCS
LLPLRPKQCK NLYTGKRSGA KKTKELQLVA KEDTDSTRDP SSQVQFPTHR AEPPCQSVHQ
EFNSGDINAR SLQDAGNSQS SALNQRGIMS KKSVLSGDQE EPVGLPAPDS EILQLPGTQG
CPRCPELQKE IEDLRKQLSA LQAVSEKFQT HLS
