CX33_MICUN
ID CX33_MICUN Reviewed; 282 AA.
AC P51916;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Gap junction Cx32.7 protein;
DE AltName: Full=Connexin-32.7;
OS Micropogonias undulatus (Atlantic croaker).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Eupercaria; Sciaenidae; Micropogonias.
OX NCBI_TaxID=29154;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC TISSUE=Ovary;
RX PubMed=7803621; DOI=10.1095/biolreprod51.3.493;
RA Yoshizaki G., Patino R., Thomas P.;
RT "Connexin messenger ribonucleic acids in the ovary of Atlantic croaker:
RT molecular cloning and characterization, hormonal control, and correlation
RT with appearance of oocyte maturational competence.";
RL Biol. Reprod. 51:493-503(1994).
CC -!- FUNCTION: One gap junction consists of a cluster of closely packed
CC pairs of transmembrane channels, the connexons, through which materials
CC of low MW diffuse from one cell to a neighboring cell.
CC -!- SUBUNIT: A connexon is composed of a hexamer of connexins.
CC -!- SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein. Cell
CC junction, gap junction.
CC -!- TISSUE SPECIFICITY: Expressed equally in incompetent and competent
CC ovaries.
CC -!- SIMILARITY: Belongs to the connexin family. Alpha-type (group II)
CC subfamily. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; L31541; AAA66970.1; -; mRNA.
DR PIR; I50996; I50996.
DR AlphaFoldDB; P51916; -.
DR SMR; P51916; -.
DR GO; GO:0005922; C:connexin complex; IEA:InterPro.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0007154; P:cell communication; IEA:InterPro.
DR Gene3D; 1.20.1440.80; -; 1.
DR InterPro; IPR000500; Connexin.
DR InterPro; IPR019570; Connexin_CCC.
DR InterPro; IPR017990; Connexin_CS.
DR InterPro; IPR013092; Connexin_N.
DR InterPro; IPR038359; Connexin_N_sf.
DR PANTHER; PTHR11984; PTHR11984; 1.
DR Pfam; PF00029; Connexin; 1.
DR PRINTS; PR00206; CONNEXIN.
DR SMART; SM00037; CNX; 1.
DR SMART; SM01089; Connexin_CCC; 1.
DR PROSITE; PS00407; CONNEXINS_1; 1.
DR PROSITE; PS00408; CONNEXINS_2; 1.
PE 2: Evidence at transcript level;
KW Cell junction; Cell membrane; Gap junction; Membrane; Transmembrane;
KW Transmembrane helix.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250"
FT CHAIN 2..282
FT /note="Gap junction Cx32.7 protein"
FT /id="PRO_0000057846"
FT TOPO_DOM 2..13
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 14..36
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 37..76
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..99
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 100..148
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 149..171
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 172..203
FT /note="Extracellular"
FT /evidence="ECO:0000255"
FT TRANSMEM 204..226
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 227..282
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 282 AA; 32690 MW; 63F531BE41D6EA4D CRC64;
MGEWDLLGRL LDKVQSHSTV IGKVWLTVLF VFRILVLRTG ADRVWGDEQS DFVCNTQQPG
CENVCYDLAF PISHVRFWFL QIIAVATPKL LYLGHVLHVI HAEKKMKERM KKQAELDDQT
NLFLRKAYKV PKYTKSSGKI SIRGRLLRSY VYHLVAKIIL EVLFIVGQYF LYGFTLDTRY
VCTRFPCPHK VDCFLSRPTE KSVIIWFMLV AAFVSLFLSL VELFYLCVKA AKECMARRQD
YTVTPVTPPL LARKSFKSHK EVFQNCVNEP ASPENNMEEV HI
