CX53_CONCL
ID CX53_CONCL Reviewed; 28 AA.
AC D6C4J9;
DT 25-JAN-2012, integrated into UniProtKB/Swiss-Prot.
DT 13-JUL-2010, sequence version 1.
DT 25-MAY-2022, entry version 18.
DE RecName: Full=Conotoxin Cl5.3 {ECO:0000303|PubMed:20363338};
DE Flags: Precursor;
OS Californiconus californicus (California cone) (Conus californicus).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Caenogastropoda; Neogastropoda; Conoidea; Conidae; Californiconus.
OX NCBI_TaxID=1736779;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=20363338; DOI=10.1016/j.ympev.2010.03.029;
RA Biggs J.S., Watkins M., Puillandre N., Ownby J.P., Lopez-Vera E.,
RA Christensen S., Moreno K.J., Bernaldez J., Licea-Navarro A., Corneli P.S.,
RA Olivera B.M.;
RT "Evolution of Conus peptide toxins: analysis of Conus californicus Reeve,
RT 1844.";
RL Mol. Phylogenet. Evol. 56:1-12(2010).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:20363338}.
CC -!- TISSUE SPECIFICITY: Expressed by the venom duct.
CC {ECO:0000305|PubMed:20363338}.
CC -!- DOMAIN: The cysteine framework is V (CC-CC). {ECO:0000305}.
CC -!- PTM: Contains 2 disulfide bonds that can be either 'C1-C3, C2-C4' or
CC 'C1-C4, C2-C3', since these disulfide connectivities have been observed
CC for conotoxins with cysteine framework V (for examples, see AC P0DQQ7
CC and AC P81755). {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the conotoxin T superfamily. {ECO:0000305}.
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DR EMBL; FJ959141; ADB93111.1; -; Genomic_DNA.
DR AlphaFoldDB; D6C4J9; -.
DR ConoServer; 4026; Cal5.3 precursor.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE 3: Inferred from homology;
KW Disulfide bond; Neurotoxin; Secreted; Toxin.
FT PEPTIDE 1..27
FT /note="Conotoxin Cl5.3"
FT /id="PRO_0000414966"
SQ SEQUENCE 28 AA; 3051 MW; 1362F5BEAAAF6623 CRC64;
NSEDGSPYPG PGQQPNCCKW PIVTCCNR