CX5C1_ARATH
ID CX5C1_ARATH Reviewed; 64 AA.
AC O22912;
DT 07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 126.
DE RecName: Full=Probable cytochrome c oxidase subunit 5C-1;
DE AltName: Full=Cytochrome c oxidase polypeptide Vc-1;
GN OrderedLocusNames=At2g47380; ORFNames=T8I13.22;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RC STRAIN=cv. Landsberg erecta;
RX PubMed=14671022; DOI=10.1105/tpc.016055;
RA Heazlewood J.L., Tonti-Filippini J.S., Gout A.M., Day D.A., Whelan J.,
RA Millar A.H.;
RT "Experimental analysis of the Arabidopsis mitochondrial proteome highlights
RT signaling and regulatory components, provides assessment of targeting
RT prediction programs, and indicates plant-specific mitochondrial proteins.";
RL Plant Cell 16:241-256(2004).
CC -!- FUNCTION: This protein is one of the nuclear-coded polypeptide chains
CC of cytochrome c oxidase, the terminal oxidase in mitochondrial electron
CC transport. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 5C family.
CC {ECO:0000305}.
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DR EMBL; AC002337; AAB63838.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10834.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62727.1; -; Genomic_DNA.
DR EMBL; AY070752; AAL50091.1; -; mRNA.
DR EMBL; AY093734; AAM10358.1; -; mRNA.
DR PIR; E84914; E84914.
DR RefSeq; NP_001324866.1; NM_001337259.1.
DR RefSeq; NP_182260.1; NM_130306.3.
DR AlphaFoldDB; O22912; -.
DR SMR; O22912; -.
DR IntAct; O22912; 1.
DR STRING; 3702.AT2G47380.1; -.
DR PaxDb; O22912; -.
DR PRIDE; O22912; -.
DR ProteomicsDB; 220425; -.
DR DNASU; 819351; -.
DR EnsemblPlants; AT2G47380.1; AT2G47380.1; AT2G47380.
DR EnsemblPlants; AT2G47380.2; AT2G47380.2; AT2G47380.
DR GeneID; 819351; -.
DR Gramene; AT2G47380.1; AT2G47380.1; AT2G47380.
DR Gramene; AT2G47380.2; AT2G47380.2; AT2G47380.
DR KEGG; ath:AT2G47380; -.
DR Araport; AT2G47380; -.
DR TAIR; locus:2065185; AT2G47380.
DR eggNOG; ENOG502S8H1; Eukaryota.
DR HOGENOM; CLU_177335_1_0_1; -.
DR InParanoid; O22912; -.
DR OMA; KEICIGA; -.
DR OrthoDB; 1619997at2759; -.
DR PhylomeDB; O22912; -.
DR BioCyc; ARA:AT2G47380-MON; -.
DR BioCyc; MetaCyc:AT2G47380-MON; -.
DR PRO; PR:O22912; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22912; baseline and differential.
DR Genevisible; O22912; AT.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005746; C:mitochondrial respirasome; IEA:InterPro.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR InterPro; IPR008432; COX5C.
DR PANTHER; PTHR34372; PTHR34372; 1.
DR PIRSF; PIRSF038131; COX5C; 1.
PE 1: Evidence at protein level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..64
FT /note="Probable cytochrome c oxidase subunit 5C-1"
FT /id="PRO_0000128185"
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 64 AA; 7070 MW; 3B74998713E8B533 CRC64;
MAGHKVAHAT LKGPSVVKEL FIGLALGLAA GGLWKMHHWN EQRKTRTFYD LLERGEISVV
AAEE