ID   CX6B1_MACFA             Reviewed;          87 AA.
AC   Q4R374;
DT   11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Cytochrome c oxidase subunit 6B1;
DE   AltName: Full=Cytochrome c oxidase subunit VIb isoform 1;
DE            Short=COX VIb-1;
GN   Name=COX6B1; ORFNames=QtsA-19092;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   International consortium for macaque cDNA sequencing and analysis;
RT   "DNA sequences of macaque genes expressed in brain or testis and its
RT   evolutionary implications.";
RL   Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Connects the two COX monomers into the physiological dimeric
CC       form. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
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DR   EMBL; AB179393; BAE02444.1; -; mRNA.
DR   RefSeq; XP_005588933.1; XM_005588876.1.
DR   RefSeq; XP_005588934.1; XM_005588877.2.
DR   AlphaFoldDB; Q4R374; -.
DR   SMR; Q4R374; -.
DR   STRING; 9541.XP_005588933.1; -.
DR   Ensembl; ENSMFAT00000016431; ENSMFAP00000042151; ENSMFAG00000039862.
DR   GeneID; 102143756; -.
DR   KEGG; mcf:102143756; -.
DR   VEuPathDB; HostDB:ENSMFAG00000039862; -.
DR   eggNOG; KOG3057; Eukaryota.
DR   GeneTree; ENSGT00940000156204; -.
DR   OMA; CPNEWIA; -.
DR   OrthoDB; 1586678at2759; -.
DR   Proteomes; UP000233100; Chromosome 19.
DR   Bgee; ENSMFAG00000039862; Expressed in heart and 13 other tissues.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR   GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IEA:Ensembl.
DR   CDD; cd00926; Cyt_c_Oxidase_VIb; 1.
DR   Gene3D; 1.10.10.140; -; 1.
DR   InterPro; IPR003213; Cyt_c_oxidase_su6B.
DR   InterPro; IPR036549; Cyt_c_oxidase_su6B_sf.
DR   PANTHER; PTHR11387; PTHR11387; 1.
DR   Pfam; PF02297; COX6B; 1.
DR   PIRSF; PIRSF000278; Cyt_c_oxidase_6B; 1.
DR   SUPFAM; SSF47694; SSF47694; 1.
DR   PROSITE; PS51808; CHCH; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Mitochondrion; Reference proteome.
FT   CHAIN           1..87
FT                   /note="Cytochrome c oxidase subunit 6B1"
FT                   /id="PRO_0000194913"
FT   DOMAIN          28..74
FT                   /note="CHCH"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           31..41
FT                   /note="Cx9C motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   MOTIF           55..66
FT                   /note="Cx10C motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        31..66
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT   DISULFID        41..55
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ   SEQUENCE   87 AA;  10318 MW;  E9D30F7CA2230396 CRC64;
     MAEEDIETKI KNYKTAPFDS RFPNQNQTRN CWQNYLDFHR CQKAMTTKGG NVSVCEWYQR
     VYQSLCPTSW VTDWDEQRAE GTFPGKI