CX6B1_MACMU
ID CX6B1_MACMU Reviewed; 87 AA.
AC Q53CG4;
DT 11-OCT-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=Cytochrome c oxidase subunit 6B1;
DE AltName: Full=Cytochrome c oxidase subunit VIb isoform 1;
DE Short=COX VIb-1;
GN Name=COX6B1; Synonyms=COX6B;
OS Macaca mulatta (Rhesus macaque).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9544;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=15851671; DOI=10.1073/pnas.0409714102;
RA Schmidt T.R., Wildman D.E., Uddin M., Opazo J.C., Goodman M.,
RA Grossman L.I.;
RT "Rapid electrostatic evolution at the binding site for cytochrome c on
RT cytochrome c oxidase in anthropoid primates.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:6379-6384(2005).
CC -!- FUNCTION: Connects the two COX monomers into the physiological dimeric
CC form. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space {ECO:0000250}.
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DR EMBL; AY585854; AAW03183.1; -; mRNA.
DR RefSeq; NP_001035371.1; NM_001040281.1.
DR RefSeq; XP_014979051.1; XM_015123565.1.
DR AlphaFoldDB; Q53CG4; -.
DR SMR; Q53CG4; -.
DR STRING; 9544.ENSMMUP00000022035; -.
DR Ensembl; ENSMMUT00000023552; ENSMMUP00000022035; ENSMMUG00000055747.
DR Ensembl; ENSMMUT00000098278; ENSMMUP00000065481; ENSMMUG00000055747.
DR GeneID; 692062; -.
DR KEGG; mcc:692062; -.
DR CTD; 1340; -.
DR VEuPathDB; HostDB:ENSMMUG00000055747; -.
DR eggNOG; KOG3057; Eukaryota.
DR GeneTree; ENSGT00940000156204; -.
DR HOGENOM; CLU_133964_3_1_1; -.
DR InParanoid; Q53CG4; -.
DR OMA; CPNEWIA; -.
DR OrthoDB; 1586678at2759; -.
DR TreeFam; TF105065; -.
DR Proteomes; UP000006718; Chromosome 19.
DR Bgee; ENSMMUG00000055747; Expressed in heart and 22 other tissues.
DR ExpressionAtlas; Q53CG4; baseline.
DR GO; GO:0005743; C:mitochondrial inner membrane; IBA:GO_Central.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0045277; C:respiratory chain complex IV; IBA:GO_Central.
DR CDD; cd00926; Cyt_c_Oxidase_VIb; 1.
DR Gene3D; 1.10.10.140; -; 1.
DR InterPro; IPR003213; Cyt_c_oxidase_su6B.
DR InterPro; IPR036549; Cyt_c_oxidase_su6B_sf.
DR PANTHER; PTHR11387; PTHR11387; 1.
DR Pfam; PF02297; COX6B; 1.
DR PIRSF; PIRSF000278; Cyt_c_oxidase_6B; 1.
DR SUPFAM; SSF47694; SSF47694; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 3: Inferred from homology;
KW Disulfide bond; Mitochondrion; Reference proteome.
FT CHAIN 1..87
FT /note="Cytochrome c oxidase subunit 6B1"
FT /id="PRO_0000194914"
FT DOMAIN 28..74
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 31..41
FT /note="Cx9C motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 55..66
FT /note="Cx10C motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 31..66
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 41..55
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ SEQUENCE 87 AA; 10318 MW; E9D30F7CA2230396 CRC64;
MAEEDIETKI KNYKTAPFDS RFPNQNQTRN CWQNYLDFHR CQKAMTTKGG NVSVCEWYQR
VYQSLCPTSW VTDWDEQRAE GTFPGKI
