CX6B2_ARATH
ID CX6B2_ARATH Reviewed; 78 AA.
AC Q945L0; Q8LD51;
DT 21-SEP-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Cytochrome c oxidase subunit 6b-2;
DE Short=AtCOX6b-2;
GN Name=COX6B-2; OrderedLocusNames=At5g57815; ORFNames=MTI20.5;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT features of the regions of 1,367,185 bp covered by 19 physically assigned
RT P1 and TAC clones.";
RL DNA Res. 5:203-216(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [7]
RP GENE FAMILY, NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=11250078; DOI=10.1016/s0378-1119(01)00334-1;
RA Ohtsu K., Nakazono M., Tsutsumi N., Hirai A.;
RT "Characterization and expression of the genes for cytochrome c oxidase
RT subunit VIb (COX6b) from rice and Arabidopsis thaliana.";
RL Gene 264:233-239(2001).
CC -!- FUNCTION: This protein is one of the nuclear-coded polypeptide chains
CC of cytochrome c oxidase, the terminal oxidase in mitochondrial electron
CC transport. This protein may be one of the heme-binding subunits of the
CC oxidase.
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}.
CC -!- TISSUE SPECIFICITY: Specifically expressed in roots.
CC {ECO:0000269|PubMed:11250078}.
CC -!- SIMILARITY: Belongs to the cytochrome c oxidase subunit 6B (TC 3.D.4.8)
CC family. {ECO:0000305}.
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DR EMBL; AB013396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED96955.1; -; Genomic_DNA.
DR EMBL; AF412096; AAL06549.1; -; mRNA.
DR EMBL; AY113061; AAM47369.1; -; mRNA.
DR EMBL; AK117656; BAC42309.1; -; mRNA.
DR EMBL; AK228364; BAF00303.1; -; mRNA.
DR EMBL; AY086201; AAM64280.1; -; mRNA.
DR RefSeq; NP_568867.1; NM_125166.5.
DR AlphaFoldDB; Q945L0; -.
DR SMR; Q945L0; -.
DR STRING; 3702.AT5G57815.1; -.
DR PaxDb; Q945L0; -.
DR PRIDE; Q945L0; -.
DR ProteomicsDB; 220325; -.
DR EnsemblPlants; AT5G57815.1; AT5G57815.1; AT5G57815.
DR GeneID; 835891; -.
DR Gramene; AT5G57815.1; AT5G57815.1; AT5G57815.
DR KEGG; ath:AT5G57815; -.
DR Araport; AT5G57815; -.
DR TAIR; locus:505006698; AT5G57815.
DR eggNOG; KOG3057; Eukaryota.
DR HOGENOM; CLU_133964_2_0_1; -.
DR InParanoid; Q945L0; -.
DR OMA; VQRWNQQ; -.
DR OrthoDB; 1586678at2759; -.
DR PhylomeDB; Q945L0; -.
DR PRO; PR:Q945L0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q945L0; baseline and differential.
DR Genevisible; Q945L0; AT.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR GO; GO:0009536; C:plastid; HDA:TAIR.
DR GO; GO:0045277; C:respiratory chain complex IV; IEA:InterPro.
DR CDD; cd00926; Cyt_c_Oxidase_VIb; 1.
DR Gene3D; 1.10.10.140; -; 1.
DR InterPro; IPR003213; Cyt_c_oxidase_su6B.
DR InterPro; IPR036549; Cyt_c_oxidase_su6B_sf.
DR Pfam; PF02297; COX6B; 1.
DR PIRSF; PIRSF000278; Cyt_c_oxidase_6B; 1.
DR SUPFAM; SSF47694; SSF47694; 1.
DR PROSITE; PS51808; CHCH; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Mitochondrion; Reference proteome.
FT CHAIN 1..78
FT /note="Cytochrome c oxidase subunit 6b-2"
FT /id="PRO_0000412234"
FT DOMAIN 22..65
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 25..35
FT /note="Cx9C motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 46..57
FT /note="Cx10C motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 25..57
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 35..46
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT CONFLICT 31
FT /note="E -> K (in Ref. 6; AAM64280)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 78 AA; 9254 MW; 677059BBBF591B0C CRC64;
MEDEIELKTA PADFRFPTTN QTRHCFTRYI EFHRCTTAKG EESNDCERFA KYYRALCPGE
WVDKWNEQRE SGTFPGPL
