ID   CYAY_BURCJ              Reviewed;         108 AA.
AC   B4E5Z6;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Iron-sulfur cluster assembly protein CyaY {ECO:0000255|HAMAP-Rule:MF_00142};
GN   Name=cyaY {ECO:0000255|HAMAP-Rule:MF_00142};
GN   OrderedLocusNames=BceJ2315_02750; ORFNames=BCAL0273;
OS   Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS   NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=216591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610;
RX   PubMed=18931103; DOI=10.1128/jb.01230-08;
RA   Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA   Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA   Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA   Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA   Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA   Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT   "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT   cystic fibrosis patients.";
RL   J. Bacteriol. 191:261-277(2009).
CC   -!- FUNCTION: Involved in iron-sulfur (Fe-S) cluster assembly. May act as a
CC       regulator of Fe-S biogenesis. {ECO:0000255|HAMAP-Rule:MF_00142}.
CC   -!- SIMILARITY: Belongs to the frataxin family. {ECO:0000255|HAMAP-
CC       Rule:MF_00142}.
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DR   EMBL; AM747720; CAR50583.1; -; Genomic_DNA.
DR   RefSeq; WP_006482891.1; NC_011000.1.
DR   PDB; 4JPD; X-ray; 1.90 A; A=1-108.
DR   PDBsum; 4JPD; -.
DR   AlphaFoldDB; B4E5Z6; -.
DR   SMR; B4E5Z6; -.
DR   STRING; 216591.BCAL0273; -.
DR   EnsemblBacteria; CAR50583; CAR50583; BCAL0273.
DR   GeneID; 56556823; -.
DR   KEGG; bcj:BCAL0273; -.
DR   eggNOG; COG1965; Bacteria.
DR   HOGENOM; CLU_080880_3_0_4; -.
DR   OMA; EPMHEIW; -.
DR   OrthoDB; 1812841at2; -.
DR   BioCyc; BCEN216591:G1G1V-316-MON; -.
DR   Proteomes; UP000001035; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0008199; F:ferric iron binding; IEA:InterPro.
DR   GO; GO:0016226; P:iron-sulfur cluster assembly; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.30.920.10; -; 1.
DR   HAMAP; MF_00142; CyaY; 1.
DR   InterPro; IPR002908; Frataxin/CyaY.
DR   InterPro; IPR036524; Frataxin/CyaY_sf.
DR   InterPro; IPR020895; Frataxin_CS.
DR   Pfam; PF01491; Frataxin_Cyay; 1.
DR   SMART; SM01219; Frataxin_Cyay; 1.
DR   SUPFAM; SSF55387; SSF55387; 1.
DR   TIGRFAMs; TIGR03421; FeS_CyaY; 1.
DR   PROSITE; PS01344; FRATAXIN_1; 1.
DR   PROSITE; PS50810; FRATAXIN_2; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Iron; Metal-binding.
FT   CHAIN           1..108
FT                   /note="Iron-sulfur cluster assembly protein CyaY"
FT                   /id="PRO_1000096237"
FT   HELIX           4..26
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   STRAND          32..36
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   STRAND          39..43
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   STRAND          49..55
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   HELIX           56..58
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   STRAND          60..65
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   STRAND          68..75
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   STRAND          78..81
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   TURN            82..84
FT                   /evidence="ECO:0007829|PDB:4JPD"
FT   HELIX           88..100
FT                   /evidence="ECO:0007829|PDB:4JPD"
SQ   SEQUENCE   108 AA;  11927 MW;  CB7BFEB93996AB20 CRC64;
     MSDTEYLARA EAVLAAVERT VDVANDGDHD IDLERNGSVL TLTFENGSKI IVNLQPPMKE
     VWIAAKAGGF HYRFIDGEWR DTRTGTEFFS ALTDYATQQA GLPITFSA