ACR1_ARATH
ID ACR1_ARATH Reviewed; 477 AA.
AC Q9FHP1; O49531;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 122.
DE RecName: Full=ACT domain-containing protein ACR1 {ECO:0000305};
DE AltName: Full=Protein ACT DOMAIN REPEATS 1 {ECO:0000303|PubMed:12481063};
GN Name=ACR1 {ECO:0000303|PubMed:12481063};
GN OrderedLocusNames=At5g65890 {ECO:0000312|Araport:AT5G65890};
GN ORFNames=F6H11.30 {ECO:0000312|EMBL:CAA16674.1},
GN K14B20.6 {ECO:0000312|EMBL:BAB11136.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, SUBCELLULAR LOCATION, TISSUE
RP SPECIFICITY, INDUCTION, AND NUCLEAR LOCALIZATION SIGNAL.
RX PubMed=12481063; DOI=10.1104/pp.007484;
RA Hsieh M.-H., Goodman H.M.;
RT "Molecular characterization of a novel gene family encoding ACT domain
RT repeat proteins in Arabidopsis.";
RL Plant Physiol. 130:1797-1806(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT clones.";
RL DNA Res. 7:31-63(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: May bind amino acids. {ECO:0000303|PubMed:12481063}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000303|PubMed:12481063}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9FHP1-1; Sequence=Displayed;
CC -!- TISSUE SPECIFICITY: Expressed in flowers and siliques.
CC {ECO:0000269|PubMed:12481063}.
CC -!- INDUCTION: By cold stress. Down-regulated by salt stress.
CC {ECO:0000269|PubMed:12481063}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA16674.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AF528058; AAM93427.1; -; mRNA.
DR EMBL; AB018108; BAB11136.1; -; Genomic_DNA.
DR EMBL; AL021684; CAA16674.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED98119.1; -; Genomic_DNA.
DR EMBL; CP002688; ANM68752.1; -; Genomic_DNA.
DR EMBL; AF360256; AAK25966.1; -; mRNA.
DR EMBL; AY040070; AAK64128.1; -; mRNA.
DR PIR; T05884; T05884.
DR RefSeq; NP_001330475.1; NM_001345724.1. [Q9FHP1-1]
DR RefSeq; NP_201390.1; NM_125986.3. [Q9FHP1-1]
DR AlphaFoldDB; Q9FHP1; -.
DR STRING; 3702.AT5G65890.1; -.
DR PaxDb; Q9FHP1; -.
DR PRIDE; Q9FHP1; -.
DR ProteomicsDB; 244793; -. [Q9FHP1-1]
DR EnsemblPlants; AT5G65890.1; AT5G65890.1; AT5G65890. [Q9FHP1-1]
DR EnsemblPlants; AT5G65890.3; AT5G65890.3; AT5G65890. [Q9FHP1-1]
DR GeneID; 836718; -.
DR Gramene; AT5G65890.1; AT5G65890.1; AT5G65890. [Q9FHP1-1]
DR Gramene; AT5G65890.3; AT5G65890.3; AT5G65890. [Q9FHP1-1]
DR KEGG; ath:AT5G65890; -.
DR Araport; AT5G65890; -.
DR TAIR; locus:2152094; AT5G65890.
DR eggNOG; ENOG502QQHS; Eukaryota.
DR HOGENOM; CLU_031332_3_0_1; -.
DR InParanoid; Q9FHP1; -.
DR OMA; CIDNDAF; -.
DR OrthoDB; 514448at2759; -.
DR PhylomeDB; Q9FHP1; -.
DR PRO; PR:Q9FHP1; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FHP1; baseline and differential.
DR Genevisible; Q9FHP1; AT.
DR GO; GO:0005634; C:nucleus; ISS:TAIR.
DR GO; GO:0016597; F:amino acid binding; ISS:TAIR.
DR InterPro; IPR040217; ACR1-12.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR PANTHER; PTHR31096; PTHR31096; 1.
DR Pfam; PF01842; ACT; 1.
DR SUPFAM; SSF55021; SSF55021; 3.
DR PROSITE; PS51671; ACT; 3.
PE 2: Evidence at transcript level;
KW Alternative splicing; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..477
FT /note="ACT domain-containing protein ACR1"
FT /id="PRO_0000431455"
FT DOMAIN 38..124
FT /note="ACT 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 134..214
FT /note="ACT 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 283..358
FT /note="ACT 3"
FT /evidence="ECO:0000305|PubMed:12481063"
FT DOMAIN 361..441
FT /note="ACT 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT MOTIF 329..345
FT /note="Bipartite nuclear localization signal"
FT /evidence="ECO:0000303|PubMed:12481063"
SQ SEQUENCE 477 AA; 52977 MW; 658D93EF32ED9F2C CRC64;
MMEIAYQPRI DSEIESLVER INPPRVCVDN DSDPECTLIK VDSANKYGIL LDMVQVLADL
DLVISKCYIS SDGEWFMDVF HVTDQLGNKL TDRSLILYIQ QAICSSRTGG ITKEMQSNLK
REVQQRHVST EHTAFEITGI NRPGLLSEIS AVLSDIGCHV TAAVAWTHHE RAAMVIYLED
GFNGGPIIDP IRKAQVKDHL DTVMEAHHIV GDVSHVVVRV VEAKGVPVGW AHTERRLHEL
MYGEGDYENC FDCDCFGDRC DALWRGRCER IHVTIEACNG YSMVNVKCRD RPKLLFDTVC
ALKELQFVVF HAVAGAKGST AEQEYFIRKK NGGTLETEGQ RERLRHCLVA AISRRASQGL
KLEIRTENKM GLLSDVTRVV RENGLSITRA EMCTQGEIAV GSFYVTDVNG GETGPSEVEA
VVRELGGAVV SAVKGVGMMP RRIGSTSDSV EQDKAKSSIG RMFWSKLERL STSIRSL
