ACR2_ARATH
ID ACR2_ARATH Reviewed; 500 AA.
AC F4JWR0;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=ACT domain-containing protein ACR2 {ECO:0000305};
DE AltName: Full=Protein ACT DOMAIN REPEATS 2 {ECO:0000303|PubMed:12481063};
GN Name=ACR2 {ECO:0000303|PubMed:12481063};
GN OrderedLocusNames=At5g25320 {ECO:0000312|Araport:AT5G25320};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP FUNCTION.
RX PubMed=12481063; DOI=10.1104/pp.007484;
RA Hsieh M.-H., Goodman H.M.;
RT "Molecular characterization of a novel gene family encoding ACT domain
RT repeat proteins in Arabidopsis.";
RL Plant Physiol. 130:1797-1806(2002).
CC -!- FUNCTION: May bind amino acids. {ECO:0000303|PubMed:12481063}.
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DR EMBL; AC006258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED93426.1; -; Genomic_DNA.
DR RefSeq; NP_197914.1; NM_122441.2.
DR AlphaFoldDB; F4JWR0; -.
DR PaxDb; F4JWR0; -.
DR PRIDE; F4JWR0; -.
DR EnsemblPlants; AT5G25320.1; AT5G25320.1; AT5G25320.
DR GeneID; 832604; -.
DR Gramene; AT5G25320.1; AT5G25320.1; AT5G25320.
DR KEGG; ath:AT5G25320; -.
DR Araport; AT5G25320; -.
DR TAIR; locus:2145482; AT5G25320.
DR eggNOG; ENOG502QVHH; Eukaryota.
DR HOGENOM; CLU_031332_2_0_1; -.
DR InParanoid; F4JWR0; -.
DR OrthoDB; 514448at2759; -.
DR PhylomeDB; F4JWR0; -.
DR PRO; PR:F4JWR0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4JWR0; baseline.
DR InterPro; IPR040217; ACR1-12.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR PANTHER; PTHR31096; PTHR31096; 1.
DR Pfam; PF01842; ACT; 1.
DR SUPFAM; SSF55021; SSF55021; 3.
DR PROSITE; PS51671; ACT; 3.
PE 4: Predicted;
KW Reference proteome; Repeat.
FT CHAIN 1..500
FT /note="ACT domain-containing protein ACR2"
FT /id="PRO_0000431456"
FT DOMAIN 39..121
FT /note="ACT 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 136..213
FT /note="ACT 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT DOMAIN 298..373
FT /note="ACT 3"
FT /evidence="ECO:0000305|PubMed:12481063"
FT DOMAIN 376..459
FT /note="ACT 4"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01007"
FT REGION 450..478
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 458..476
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 500 AA; 56312 MW; CB04A44559BEFB5D CRC64;
MQKVCWPYFD PDFDNLGERI YGPPCRVYID NDSIQDCTVV KVNSENKQGL LLEVVQILTD
MNLIITKSYI SSDGGWFMDV FHVKDEHGNK LTDKSVINHI KHAIGTSRRE SDFIKASEAN
NNSLEPQLAD HGEHTAIEMT GTDRPGLFSE IFAAFADLHC NVMEAHAWSH NARLACIAYV
SDDNTHTPID DPSRLASIED HLSTVIRATA DPASNSTHVG HKENETDGFL AGQGKGCMNS
NMERRLHQLM LSVRDFDEPF CEPSSLSLLS SKLEYCDHKE RKTTIVSIGN CEERGYSIVT
VKSKDRRRLM FDTICTLVDM QYVIFHAALR SDGADAFQEY FIRHIDGRAL NTEGEKERVI
KCLEAAIERR VCEGVKLELC AENRVGLLSD ITRVLRENGL TVVRADVETQ GQKSLNAFYV
RDISGNKIDM EFVESVKKEM RPIHLEVKNE DTKIDTVGSD EPTASASATP QRQPQPHRFS
LGDILRSQME RLSLNFVPTK
